ʻO ka maʻi maʻamau - he hui pū kēia o nā maʻi hormonal a me ka metabolic, e like me: ka momona i ka ʻano ʻōpū-visceral, nā maʻi o ka carbohydrate a me ka lipid metabolism, arterial hypertension, nā maʻi hanu i ka hiamoe pō. ʻO kēia mau maʻi āpau e pili kokoke ana kekahi i kekahi, a ʻo kā lākou hui pū ʻana e hoʻoholo ai i ka hele ʻana o ka metabolic syndrome i loko o ke kanaka. ʻO kēia paʻakikī o nā pathologies e hoʻoweliweli i ke ola o ke kanaka, no laila ua kapa ʻia e ka poʻe loea he quartet make.
Laha loa ka ma'i ma waena o ka po'e makua, no laila hiki ke ho'ohālikelike 'ia ka ma'i ma'i me ka ma'i ahulau. Wahi a nā kumu like ʻole, ʻo 20-30% o nā poʻe ma waena o nā makahiki mai 20 a 49 mau makahiki i loaʻa iā ia. I kēia mau makahiki, ʻike pinepine ʻia ka metabolic syndrome i nā kāne. Ma hope o 50 mau makahiki, ua like ka nui o nā maʻi ma waena o nā kāne a me nā wahine. I ka manawa like, aia nā hōʻike e lilo ka poʻe me ka momona i 10% hou aʻe i kēlā me kēia 10 makahiki.
Hoʻopilikia maikaʻi kēia maʻi i ka holomua o nā maʻi cardiovascular e pili pū ana me ka atherosclerosis. Hoʻonui ka maʻi i ka pilikia o ka hoʻomohala ʻana i nā pilikia coronary, kahi e alakaʻi ai i ka make o nā maʻi. Inā loaʻa kekahi kanaka i ka momona, a laila piʻi ka nui o ka ulu ʻana o ka hypertension arterial i loko ona e 50% a ʻoi aku paha.
ʻOiai ʻaʻole i hoʻopau ʻia kahi hālāwai kūkā Lūkini o kahi ʻōlelo lapaʻau me ka ʻole o ke kūkākūkā ʻana o ka metabolic syndrome, i ka hoʻomaʻamaʻa, ke alo nei nā mea maʻi i ka ʻoiaʻiʻo ʻaʻole lākou e loaʻa i ka lāʻau kūpono no ko lākou kūlana. Wahi a ka ʻikepili i hāʻawi ʻia e ka State Research Center for Preventive Medicine, ʻo 20% wale nō o nā mea maʻi i hāʻawi ʻia me ka mālama antihypertensive e pono ai, ʻoiai ʻo 10% wale nō o nā mea maʻi e loaʻa i ka mālama lipid-lowering kūpono.
Nā kumu o ka metabolic syndrome
ʻO nā kumu nui o ka metabolic syndrome i manaʻo ʻia ʻo ia ka predisposition o ka mea maʻi i ka pale ʻana i ka insulin, ka nui o ka momona momona, a me ka nele o ka hana kino.
ʻO ka hana nui i ka hoʻomohala ʻana o ka maʻi maʻi no ka pale ʻana i ka insulin. ʻO kēia hormone i loko o ke kino kanaka ke kuleana no nā hana koʻikoʻi he nui, akā ʻo kāna kumu kumu e hoʻopaʻa i nā mea hoʻokipa e pili ana iā ia, aia i loko o ka membrane o kēlā me kēia cell. Ma hope o ke kamaʻilio kūpono, hoʻomaka ka hana o ka lawe ʻana i ka glucose i loko o ke kelepona. Pono ka insulin i mea e wehe ai i kēia mau "puka komo" no ka glucose. Eia nō naʻe, ke hoʻomau ʻole nā mea hoʻokipa i ka insulin, ʻaʻole hiki i ka glucose ke komo i loko o ke kelepona a hōʻiliʻili i loko o ke koko. ʻO ka insulin ponoʻī nō hoʻi e hōʻiliʻili i loko o ke kahe koko.
No laila, ʻo nā kumu o ka ulu ʻana o ka metabolic syndrome:
predisposition i ka insulin resistance
Loaʻa i kekahi poʻe kēia predisposition mai ka hānau ʻana.
ʻO ka hoʻololi ʻana o ka gene ma ka chromosome 19 e alakaʻi i kēia mau pilikia:
ʻAʻole lawa ka loaʻa ʻana o nā kelepona i ka insulin;
Loaʻa paha ka nui o nā mea loaʻa, akā nele lākou i ka naʻau o ka insulin, ka hopena o ka glucose a me ka meaʻai i waiho ʻia i loko o ke kiko adipose;
Hiki i ka ʻōnaehana pale kino kanaka ke hana i nā antibodies e ālai ana i nā mea hoʻokipa insulin-sensitive;
E hana ʻia ka insulin maʻamau e ka pancreas e kūʻē i ke ʻano o ka pau ʻana o nā mea hana o ke kino e kuleana no ka hana ʻana i ka protein beta.
Aia ma kahi o 50 mau hoʻololi gene e hiki ke alakaʻi i ka pale ʻana i ka insulin. Manaʻo nā kānaka ʻepekema ua emi iho ka naʻau o ka insulin kanaka ma muli o ka evolution, i hiki ai i kona kino ke hoʻomanawanui i ka pōloli pōkole. Ua ʻike ʻia ua pilikia pinepine ka poʻe kahiko i ka ʻai. I kēia ao, ua loli nui nā mea a pau. Ma muli o ka nui o ka ʻai ʻana i nā meaʻai momona i nā momona a me nā kilocalories, hōʻiliʻili ka momona visceral a ulu ka metabolic syndrome. Ma hope o nā mea a pau, ʻo ke kanaka hou, ma ke ʻano he kānāwai, ʻaʻole ʻike i ka nele o ka meaʻai, a ʻai ʻo ia i nā meaʻai momona.
[Video] Kauka Berg – Nānā i ka Insulin no ka Metabolic Syndrome. No ke aha he mea nui ia?