ʻO nā pūnaewele nui o ke ake, hana nā hepatocytes i kahi nui o nā hana nui: ka kānana ʻana o ke koko, ka hoʻopau ʻana i nā mea make, mālama a me ka synthes o nā kō, a pēlā aku.

ʻO ka hapanui o ke akepaʻa nā hepatocytes i hoʻonohonoho ʻia i nā ākea, ma waena o nā mea e kahe ai nā capillaries o ke koko a me nā nalu wela biliary. ʻO nā hale hana biochemical maoli, hiki i kēia mau pūnaewele ke hopu i nā toxins e kahe ana i loko o ke koko a hoʻopau i kēia mau ʻōpala i ka pā. Akā ʻaʻole kēia wale nō kā lākou hana, ʻoiai mālama lākou a hana i nā mea he nui e pono ai i ke kino: glucose, triglycerin, albumin, paʻakai bile, a pēlā aku.

Me ka ʻole o nā hepatocytes hana, ʻaʻole i ʻoi aku ke ola o ke kino i kekahi mau hola. Hāʻawi kēia mau pūnaewele i nā hana nui he nui, e like me:

• lkahi mālama kō kō : i ka hanana o hyperglycemia, hūnā ka pancreas i ka insulin, kahi e hoʻoulu ai i ka lawe ʻana a me ka mālama ʻana o ka glucose koko e nā hepeta. Hoʻohālikelike, i ka hanana o hypoglycemia, excretes glucagon, e paipai i nā hepatosit e hoʻokuʻu i kēia ikehu i ke koko;
• hoʻoheheʻe koko : Hōʻalo nā hepatocytes i ke koko o nā toxins (ka waiʻona, nā lāʻau, nā lāʻau, a pēlā aku), a laila heʻe iā lākou me ka bile; 
• ka huna o ka bile ka mea, mālama ʻia i loko o ka gallbladder, e hoʻokuʻu ʻia i loko o ka ʻōpū i ka manawa o ka digestion. Aia kēia mea i loko o ka lua i lawe ʻia mai ke koko a me nā waikawa o ka bile, hiki ke wāwahi i nā lipida i hoʻopili ʻia e ka meaʻai i loko o nā triglycerides, kekahi "wahie" o ke kino;
• ka hōʻuluʻulu o nā triglycerides mai ke kō a me ka waiʻona. ʻO kēia nā waikawa momona like i ʻōlelo ʻia ma luna. E like me lākou, no laila e lawe ʻia lākou e ke koko i nā hunaola e pono ai lākou (nā mākala, a me nā mea ʻē aʻe) a i ʻole mālama ʻia i loko o nā aʻa adipose;
• iecaianoaaiiuo o ka clotting kumumea, ʻo ia hoʻi nā protein i komo i loko o ke kāpili koko.

Hepatic steatosis

He hōʻiliʻili kēia o nā triglycerides i nā hepatocytes. Hiki i kēia pathology ke hopena i ka inu waiʻona nui akā akā - a ʻoi aku ka pinepine a ʻoi pinepine kēia hihia - hoʻomohala i nā mea maʻi i inu ʻole akā kaumaha nui a loaʻa i ka maʻi maʻamau ʻo 2. maʻi maʻi ʻona ʻona ʻona ʻole (NAFLD).

Hepatic steatosis noho asymptomat no ka manawa lōʻihi ma mua o ke kumu hepatitis. ʻO kēia ka pane hoʻāla e alakaʻi pinepine ai i ka loaʻa o ka pathology.

hepatitis

ʻO ka hoʻohaunaele o ke ake, hiki i ka maʻi hepatitis ke kumu ʻia e ka maʻi momona o ke ake, akā e ka maʻi nāna e hoʻonui i nā maʻi hepeta (hepatitis A, B a me C virus), e ka ʻona ʻona, e ka hōʻike ʻana i kahi huahana ʻawahia a i ʻole, pinepine ʻole, e ka maʻi maʻi autoimmune.

Hoʻololi nui nā ʻōuli i kēlā me kēia hihia. 

• kuni;
• lilo o ka makemake ʻole.
• pāhoehoe;
• nausea;
• hōʻoluʻolu o ka ʻōpū;
• ʻōmaʻomaʻo keʻokeʻo;
• etc.

Hiki iā lākou ke akahai a ʻino hoʻi, hele aku iā lākou iho, a hoʻomau paha. ʻO Hepatitis C, no ka laʻana, lilo i maʻi ma 80% o nā hihia, ʻoiai ʻo ka hepatitis A hiki ke hoʻoholo kūlohelohe. Hiki ke ʻike ʻole ʻia ka maʻi, a ʻike wale ʻia ma hope o ka holomua ʻana i ka cirrhosis a i ʻole ke kanesa.

ʻO Cirrhosis

Inā ʻaʻole mālama ʻia ko lākou mumū hoʻomau, pau ka make ʻana o nā hepatocytes ma hope o kekahi. Ua lilo ka hana a ke akepaʻa.

ʻO ia ke ʻano o hoʻokahi a ʻoi paha nā pilikia e alakaʻi pinepine ai i ka loaʻa ʻana o ka cirrhosis: hemorrhage digestive, ascites (ka hoʻopili ʻana o ka ʻōpū i pili i ka hōʻiliʻili ʻana o ka wai i ka lua peritoneal), jaundice (jaundice o ka ʻili a keʻokeʻo o ka maka, mimi ʻeleʻele), maʻi ʻaʻai, etc.

Kanesa maʻi ʻaʻai

ʻO ka Hepatocarcinoma, a i ʻole he hepatocellular carcinoma, hoʻomaka i kahi hepatocyte, a lilo i ʻano ʻē, hoʻomaka e hoʻonui i kahi ʻano anarchic a hana i kahi tumo malignant. Kākaʻikahi loa kēia ʻano ʻeha e kū ma ke akepaʻa i loaʻa ʻole ka steatosis, ka maʻi hepa a me ka cirrhosis.

ʻO ka pohō kaumaha ʻole i wehewehe ʻole ʻia, ka nalo ʻana o ka makemake, ka ʻeha o ka ʻōpū, ka paupau a me ka luaʻi, ka luhi nui, ke ʻano o kahi puʻupuʻu ma ke akepaʻa, keu hoʻi inā pili i ka jaundice, e makaʻala iā ʻoe. Akā e akahele: maʻamau kēia mau ʻōuli i nā maʻi maʻi ate. Hiki wale i ke kauka ke hana i ke kuhi.

Hyperplasia nodular kiko

ʻO ka hyperplasia nodular Focal ka hoʻonui ʻana i ka helu o nā hepatosit i ke ake, e hoʻonui ana i ka nui. Hiki ke ʻike ʻia nā nodule Fibrous o 1 a 10 cm. ʻO kēia mau tumors, kākaʻikahi a maikaʻi ʻole, ʻoluʻolu ʻia e ka lawe ʻana i nā ʻōpū oral a i ʻole nā ​​lāʻau e like me ka estrogen. Kākaʻikahi kā lākou pilikia. ʻO kēia ke kumu he mea maʻamau ka lawe ʻana iā lākou ma ke kaʻe.

Ma ka mālama pono ʻana a me ke kūpaʻa ʻana i nā kumu o ka hepatitis (antiviral lapaʻau, haʻalele ʻana i ka ʻalekohola, kaʻai hōʻemi kaumaha, kaohi ʻana o ka maʻi kō, a pēlā aku), hiki ke pale ʻia a paʻa paha ka cirrhosis. Inā ua luku ʻia nā kiko, ʻaʻole ia e hoʻōla, akā ʻaʻole e paʻa hou ke koena o ke ake. Inā holomua loa ka cirrhosis, hiki i kahi transplant ke hoʻihoʻi i ka hana ate maikaʻi ʻole, ke loaʻa kahi graft.

I ka hanana o ka maʻi ʻaʻai, ākea ka panela o nā mālama.

• hemo hapa o ke akepaʻa;
• holoi holoʻokoʻa ukali ʻia e kahi transplant;
• ka luku ʻia ʻana o ka tumo e nā radiofrequencies a i ʻole nā ​​microwaves;
• uila uila;
• chemotherapy;
• etc. 

Pili ka hoʻolālā hoʻolālā i nā kumu he nui, e like me ka helu o nā leona, ko lākou nui, ko lākou pae a me ke ʻano o ke ake.

Kū i mua me nā ʻōuli e hōʻike nei i kahi pathology hepatic, hōʻoia kahi hōʻoia koko i ke komo ʻana o ke ake (hypoalbuminemia, a pēlā aku.). Inā ʻaʻole ʻike ʻia kekahi mea hoʻomaʻi i loko o ke kākā koko, e kuhikuhi ʻia kahi ultrasound, pākuʻi ʻia inā pono me kahi MRI, kahi CT scan a i ʻole kahi ultrasound Doppler. E noi ʻia paha kahi biopsy i mea hoʻohui.