ʻO ka Agranulocytosis kahi maʻi like ʻole o ke koko i ʻike ʻia e ka nalo ʻana o kahi subclass o nā leukocytes: neutrophilic granulocytes. Hāʻawi i ko lākou koʻikoʻi i ka ʻōnaehana pale, pono ko lākou nalowale ʻana i ka lāʻau lapaʻau wikiwiki.

ʻO ka Agranulocytosis kahi huaʻōlelo lapaʻau i hoʻohana ʻia e kuhikuhi i kahi ʻano like ʻole o ke koko. Ua like ia me ka aneane pau loa o ka nalo ʻana o nā granulocytes neutrophil koko, i ʻike mua ʻia he koko neutrophils.

ʻO kēia mau ʻāpana koko he subclass o nā leukocytes (keʻokeʻo keʻokeʻo), nā ʻāpana koko i komo i loko o ka ʻōnaehana pale. Hōʻike kēia subclass i ka hapa nui o nā leukocytes i loko o ke koko. I loko o ke kahe koko, he kuleana koʻikoʻi nā neutrophil granulocytes no ka mea ʻo lākou ke kuleana no ka pale ʻana i nā kino haole a me nā maʻi maʻi. Hiki iā lākou ke phagocyte i kēia mau ʻāpana, ʻo ia hoʻi e hoʻomoʻa iā lākou i mea e luku ai iā lākou.

ʻO ka Agranulocytosis kahi maʻi like ʻole o ke koko i hiki ke ʻike ʻia me ka a hemogram, i kapa ʻia ʻo Blood Count and Formula (NFS). Hāʻawi kēia ho'āʻo i nā ʻike he nui e pili ana i ke koko koko. ʻO ka helu koko e hiki ai ke hoʻohālikelike i nā mea like ʻole o ke koko, kahi o nā neutrophil granulocytes i ʻāpana.

I ka wā 'ka nānā ʻana o neutrophil, ʻike ʻia kahi abnormality i ka wā e emi ai ka neʻe o kēia mau cell ma mua o 1700 / mm3, a i ʻole 1,7 g / L i ke koko. Inā haʻahaʻa loa ke kiʻekiʻe o nā granulocytes neutrophilic, ke ʻōlelo nei mākou a neutropenia.

ʻO ka Agranulocytosis kahi ʻano koʻikoʻi o neutropenia. Hōʻike ʻia ia e kahi pae haʻahaʻa loa o nā granulocytes neutrophilic, ma lalo o 500 / mm3, a i ʻole 0,5 g / L.

I ka hapanui o nā hihia, ʻo ka agranulocytosis kahi maʻi ʻino i ke koko ma hope o ka lawe ʻana i kekahi mau lāʻau lapaʻau. Ma muli o ke kumu a me nā ʻano o ka anomaly, ʻelua mau ʻano o ka agranulocytosis lāʻau lapaʻau:

• ʻO ka agranulocytosis i hoʻokomo ʻia i ka lāʻau, ʻO ka hoʻomohala ʻana ma muli o ke koho ʻana o kahi lāʻau lapaʻau, e pili ana i ka laina granulocyte wale nō;
• ʻO ka agranulocytosis i hoʻokomo ʻia i ka lāʻau i ka pōʻaiapili o ka anemia aplasticʻO ka uluʻana ma muli o kahi maʻi o ka iwi iwi, kahi iʻikeʻia e ka emiʻana o nā laina o ke koko.

I ka pōʻaiapili o ka anemia aplastic, hiki ke hoʻokaʻawale i nā ʻano agranulocytosis. ʻOiaʻiʻo, ʻo kēia maʻi koko i hōʻike ʻia e ka hoʻopau ʻana i ka hana ʻana o nā ʻāpana koko i loko o ka iwi iwi hiki ke loaʻa i kekahi mau kumu. Hiki ke noʻonoʻo ʻia ka anemia aplastic e like me:

• post-chemotherapy aplastic anemia ma hope o ka mālama ʻana i ka chemotherapy;
• anemia aplastic kuʻemaka ke kumu o kekahi mau laau.

ʻOiai ʻo ka agranulocytosis i hoʻohana ʻia i ka lāʻau e hōʻike ana ma waena o 64 a me 83% o nā hihia, hiki i kēia mau mea ʻino ke kumu ʻē aʻe. No ka hua bacteria, viral a parasitic paha, hiki i ka ma'i ma kahi pae ki'eki'e ke kumu i ka pau 'ana o nā granulocytes neutrophilic.

Hāʻawi ʻia i ka hana o nā neutrophilic granuclocytes i loko o ka ʻōnaehana pale, hoʻolaha ka agranulocytosis i ke kino i kahi pilikia nui o ka maʻi. ʻAʻole lawa ka nui o nā neutrophils e kūʻē i ka ulu ʻana o kekahi mau pathogens, hiki ke alakaʻi i kahi septicemia, a i ʻole he sepsis, he maʻi maʻamau a i ʻole ka mumū o ke kino.

ʻO nā hōʻailona o ka agranulocytosis kahi maʻi. Hiki iā ia ke hōʻike iā ia iho e nā hōʻailona infectious i kekahi mau wahi o ke kino me ka ʻōnaehana digestive, ka ENT sphere, ka pulmonary system a i ʻole ka ʻili.

Hōʻike koke ʻia ka agranulocytosis i hoʻokomo ʻia i ka lāʻau lapaʻau a hōʻike ʻia e kahi maʻi kuni kiʻekiʻe (ma luna o 38,5 ° C) i hele pū ʻia me ke anuanu. I loko o ka iwi iwi aplasia, hiki ke lohi ka ulu ʻana o ka agranulocytosis.

ʻO ka Agranulocytosis kahi maʻi ʻino o ke koko e pono e mālama koke ʻia e pale i nā pilikia. ʻOiai ʻokoʻa paha ka mālama ʻana ma muli o ke kumu o ka agranulocytosis, ua hoʻokumu ʻia kāna hoʻokele ma:

• hoʻokaʻawale i loko o ka haukapila no ka pale ʻana i ka mea maʻi;
• ka hoʻomaka ʻana o ka lāʻau antibiotic e mālama i nā maʻi;
• ka hoʻohana ʻana i nā mea ulu granulocyte e hoʻoulu i ka hana o nā granulocytes neutrophilic.