Ma luna o nā mea a pau, pono e hoʻomanaʻo he manaʻo maʻamau ka hopohopo, e ʻike ʻia ke manaʻo kekahi i ka hoʻoweliweli a i ʻole ka pilikia. E lilo ia i mea pōʻino a pilikia ke hōʻike ʻia ʻo ia ma mua o ka hoʻoweliweli maoli a hoʻomau paha no ka manawa lōʻihi, no laila ke keʻakeʻa nei i nā hana o kēlā me kēia lā a me ka hana o ke kanaka.

ʻAʻole maopopo i nā kumu o nā pilikia hopohopo. Hoʻopili lākou i nā mea genetic, physiological a me ka nohona.

No laila, ʻike mākou he ʻoi aku ka pilikia o ke kanaka e hōʻike i nā maʻi hopohopo inā loaʻa kekahi o kona ʻohana. ʻIke ʻia ʻo ka wahine he kumu pilikia no ka maʻi hopohopo.

ʻO ka loaʻa ʻana o nā hanana koʻikoʻi a ʻeha paha, ʻoi aku hoʻi i ka wā kamaliʻi, a i ʻole ka loaʻa ʻana o kahi maʻi psychiatric ʻē aʻe (ka maʻi bipolar, no ka laʻana) hiki ke hoʻoikaika i nā maʻi hopohopo.

ʻO ka mea hope loa, ʻike mākou ua pili ka hiki ʻana o kahi maʻi hopohopo, i waena o nā mea ʻē aʻe, i nā pilikia physiological i loko o ka lolo, ʻo ia hoʻi i kekahi mau neurotransmitters, ʻo kēia mau mea e lawelawe nei ma ke ʻano he mau ʻelele no nā neʻe nerve mai kekahi neuron a i kekahi. 'ē aʻe. ʻO ke kikoʻī, ʻo GABA (ka mea paʻa nui o nā overreactions āpau o nā neurons), norepinephrine a me serotonin e pili ana.⁵. ʻO nā lāʻau lapaʻau no nā maʻi hopohopo e hana pololei i ka hoʻoponopono ʻana o kēia mau neurotransmitters. ʻO Cortisol (ka hormone stress) kekahi kuleana.