ʻO ka maʻi Cytomegalovirus i loko o ka wahine hāpai hiki ke hana i nā deformities i ka pēpē inā loaʻa ka maʻi. ʻO ia ke kumu he mea nui e ʻike inā pilikia ʻoe i ka loaʻa ʻana o kēia maʻi a mālama iā ʻoe iho me nā lula maʻemaʻe inā ʻo ia ka hihia.

ʻO Cytomegalovirus kahi maʻi o ka ʻohana herpesvirus (Herpesviridae). Ua haumia ʻia e ka pili ʻana me ke kohu, nā waimaka a i ʻole ka mimi, a i ʻole nā ​​​​mea huna o ke kino, akā ma ke kuhi ʻana hoʻi i ka wā ʻuʻu. Loaʻa pinepine kēia maʻi i ka wā kamaliʻi.

ʻO ka maʻi Cytomegalovirus ka maʻi maʻamau o ka makuahine-fetal.

ʻO ka hapa nui o nā wahine hāpai i loaʻa i ka maʻi cytomegalovirus i ka wā kamaliʻi. Hāʻawi lākou i nā antibodies e kūʻē i ka maʻi. Hiki iā lākou ke hoʻāla hou i ka maʻi i ka wā hāpai akā haʻahaʻa loa ka pilikia o ka hoʻouna ʻana i ka pēpē. No nā makuahine ʻē aʻe, hōʻike kēia maʻi i kahi pōʻino inā loaʻa ia no ka manawa mua (maʻi maʻi mua) i ka makahiki mua o ka hāpai ʻana a hiki i ka 27 pule o ka amenorrhea (27 WA a i ʻole 25 pule o ka hāpai ʻana). I ka hihia o ka maʻi mua o ka makuahine, ua hoʻouna ʻia ka palaka ma o ke koko i ka pēpē i ka hapalua o nā hihia. Hiki i ka Cytomegalovirus ke hoʻolōʻihi i ka ulu ʻana, ka lolo, a me ke kuli, akā ʻo ka hapa nui o nā pēpē me ka maʻi cytomegalovirus congenital ʻaʻohe hōʻailona ke hānau ʻia. Eia nō naʻe, hiki i kahi helu liʻiliʻi o nā pēpē i hānau ʻia me ka ʻole o ka pōʻino hiki ke hoʻomohala i nā sequelae sensorineural ma mua o ka makahiki 2.

Cytomegalovirus: he aha kou kūlana immunological?

ʻO kahi hoʻāʻo koko i lawe ʻia i ka hoʻomaka ʻana o ka hāpai ʻana e hiki ke ʻike i ke kūlana immunological e pili ana i ka cytomegalovirus. Inā hōʻike ka serodiagnosis i ka nele o nā antibodies, pono ʻoe e hahai i nā kūlana maʻemaʻe i ka wā o kou hāpai ʻana e pale i ka cytomegalovirus.

Ua hana ʻia nā serodiagnoses i ka wā hāpai e ʻike ai inā ʻaʻole i loaʻa i ka wahine hāpai ka maʻi cytomegalovirus. Inā pēlā, hiki iā lākou ke hoʻonohonoho i ka nānā ʻana i ka fetal. ʻAʻole ʻōlelo ʻia e nā luna olakino o ka lehulehu ka nānā ʻana i nā maʻi cytomegalovirus i ka wā hāpai. ʻOiaʻiʻo, ʻaʻohe lāʻau lapaʻau a makaʻu hoʻi ka poʻe ʻoihana olakino i ka overdiagnosis a me ka hoʻihoʻi nui ʻana i ka hoʻopau manawaleʻa a i ʻole ka lāʻau lapaʻau. Manaʻo ʻia ka nānā ʻana serologic no CMV i nā wahine e hoʻomohala ana i nā hōʻailona like-flu i ka wā hāpai a i ʻole ma hope o nā hōʻailona ultrasound e hōʻike ana i ka maʻi CMV.

ʻAʻole hāʻawi pinepine ka maʻi CMV i kahi kanaka makua, akā hiki i ka CMV ke hāʻawi i kahi maʻi viral e like me ka maʻi maʻi. ʻO nā hōʻailona nui: ke kuni, ke poʻo, ka luhi nui, ka nasopharyngitis, nā lymph nodes, etc.

Ua loaʻa iā ʻoe kahi maʻi cytomegalovirus ma mua o 27 pule? No ka ʻike inā pili ʻia kāu pēpē, hoʻonohonoho ʻia ka nānā ʻana i ka ultrasound. Hiki ke lawe ʻia kahi laʻana o ka wai amniotic (amniocentesis) mai 22 pule i mea e ʻike ai inā aia ka maʻi i loko o ka wai amniotic.

Inā maʻamau ka ultrasound a ʻaʻole i loaʻa i ka wai amniotic ka maʻi, he mea hōʻoluʻolu! Eia nō naʻe, e mālama ʻia ka nānā ʻana o ka ultrasound i ka wā o ka hāpai ʻana a e nānā ʻia ka pēpē no CMV i ka wā hānau.

Inā hōʻike ka ultrasound i kahi ʻano ʻino e hōʻike ana i ka maʻi CMV (hoʻemi i ka ulu ʻana, hydrocephalus (hoʻuluʻulu ʻana o ka wai i loko o ka iwi poʻo) a aia ka maʻi i loko o ka wai amniotic, loaʻa ka pōʻino nui i ka pēpē. oe.

Inā loaʻa ka maʻi maʻi i loko o ka wai amniotic akā ʻo ka ultrasound maʻamau, ʻaʻole hiki ke ʻike inā ua maʻi ka pēpē a ʻaʻole paha. Hiki ke hoʻomau ka hāpai ʻana me ka nānā ʻana i ka ultrasound.

No ka pale ʻana i kāu pēpē i loko o ka ʻōpū, he mea nui e hōʻemi i ka pilikia o ka loaʻa ʻana o ka cytomegalovirus inā pilikia ʻoe. Ma muli o ka lawe pinepine ʻia ʻana o ka cytomegalovirus e nā keiki ma lalo o 3 mau makahiki, inā ʻoe e launa pū me nā keiki liʻiliʻi i ka wā o kou hāpai ʻana (ʻo ʻoe iho a i kāu hana paha) e holoi pono i kou mau lima ma hope o ka hoʻololi ʻana. nā diapers a i ʻole holoi ʻia i nā mea huna a mai kaʻana like i kāu ʻoki ʻoki me lākou. ʻAʻole pono e honi i nā keiki liʻiliʻi ma ka waha.

Ka pale ʻana a me ka mālama ʻana i ka cytomegalovirus i loko o ka ʻōpū?

Ke aʻo ʻia nei ʻelua mau lāʻau lapaʻau no ka maʻi CMV congenital:

• lāʻau antiretroviral therapy
• he lāʻau lapaʻau e hoʻokomo i nā immunoglobulin anti-CMV kūikawā

ʻO ka pahuhopu o kēia mau lāʻau lapaʻau ʻo ia ka hoʻemi ʻana i ka nui o ka hoʻouna ʻana i ka pēpē i ka wā e loaʻa ai ka maʻi makuahine a e hoʻemi i ka nui o ka hopena i ka wā o ka maʻi fetal.

Ke noiʻi ʻia nei kekahi lāʻau lapaʻau CMV i hiki ke hāʻawi ʻia i ka wā hāpai mua i nā wahine maʻi HIV maikaʻi ʻole no ka maʻi CMV.