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ʻO nā platelets nā mea o ke koko e hana nui i ka coagulation, ʻo ia hoʻi ke kūkulu ʻana i kahi clot e hiki ai ke hoʻōki i ka hemorrhage i ka wā e haki ai ka paia o kahi kīʻaha koko. Hōʻike ka mean platelet volume, a i ʻole MPV, i ka nui awelika o nā platelets i loko o ke kanaka. ʻAʻole i unuhi ʻia ka hopena MPV ma ka noʻonoʻo ʻana i ka helu o nā platelets, akā ʻo nā ʻikepili ʻē aʻe a me ka helu koko. Hiki ke hoʻololi ʻia i kekahi mau pathologies, ʻoiai inā loaʻa nā pilikia cardiovascular a me ka thrombosis, akā hiki ke hoʻololi ʻia i ka physiologically a me ka pili ʻole ʻana i kahi maʻi.
Mean platelet volume (MPV)
Hoʻoholo ʻia ka MPV ma muli o ka histogram mahele platelet. ʻO ka mea pōʻino, ʻaʻole i noʻonoʻo ʻia ka MPV i ka hana lapaʻau a, ʻoi aku hoʻi, i ka ʻike ʻana i ka anemia. Eia nō naʻe, e like me ka mea hōʻike mua, hiki ke hoʻopili i ka wehewehe ʻana o ka pathology i ʻike ʻia a kōkua i ka ʻike ʻana i ka thrombocytopathy (micro- or macrothrombocytosis) i ka anemia hereditary a i ʻole nā maʻi ʻē aʻe.
Ma ka loiloi ʻana i ka MPV, hiki i kekahi ke ʻike:
- hoʻonui i ka platelet aggregation a me ka thrombosis;
- ke kahe koko ikaika ma ka ʻike ʻana i nā platelets nui i nā maʻi me ka anemia deficiency hao;
- Hiki ke hoʻohana ʻia ka MPV ma ke ʻano he hōʻailona hou no ka maʻi myeloproliferative mau loa (nā platelets nui).
Kahi manawa kūmole: 7.6-9.0 fL
ke kiekie Hōʻike nā helu MPV i ka hele ʻana o nā platelets nui, me nā ʻōpio.
Hoʻoemiʻia Hōʻike nā helu MPV i ka hele ʻana o nā platelet liʻiliʻi i ke koko.
He aha ke ʻano o ka nui o ka platelet (MPV)?
ka MPV, mean platelet volume, he a papa kuhikuhi helu platelet, ʻo ia nā mea liʻiliʻi o ke koko a ʻoi aku ka nui o nā mea hoʻoiho. Kapa ʻia nā pāpale he thrombosit.
- Pono pono nā platelet no ka hoʻopili ʻana i ke koko. Komo lākou i ka hoʻōki ʻana i ke kahe ʻana i ka wā o ka hoʻololi o ka paia o nā kīʻaha koko (nā aʻa a me nā uaua). Hoʻoikaika lākou i ka hanana o ke kahe kūloko e like me ka hanana o ke kahe o waho;
- Hana ʻia nā pālolo i loko o ka iwi iwi, ma loko kahi e puka mai ai kahi pūnaewele nui (i kapa ʻia he megakaryocyte) i mau ʻāpana liʻiliʻi liʻiliʻi. ʻO kēia mau ʻāpana, i kapa ʻia nā platelet, lilo i mea hana ke komo lākou i ke kahe o ke koko;
- Hiki ke helu i nā platelet, akā e ana nō hoʻi i kā lākou leo ma o ka mea kālailai e hoʻohana ana i ke kaola māmā.
ʻOi aku ka liʻiliʻi o ka mau platelet nui, a ua hoʻokuʻu ʻia ma mua o ka maʻamau mai ka iwi o ka iwi. Kūkākūkā, ʻoi aku ka nui o nā platelet liʻiliʻi ma mua o ka awelika.
I ka maʻamau, aia ka pilina ma waena o ka mean platelet volume (MPV) a me ka helu o nā platelets. No laila, aia kahi hoʻoponopono kūlohelohe o ka nui o ka platelet mass (ka hui pū ʻana o ka helu a me ka nui o nā platelets). Hōʻike kēia i ka emi ʻana o ka nui o nā platelets e hoʻoulu ai i nā megakaryocytes e ka thrombopoietin, ka hopena i ka hana ʻana o nā platelets nui.
- ʻO ka pae maʻamau o nā platelet i loko o ke koko (kā lākou nui) aia ma waena o 150 a me 000 platelet ma ka millimeter millimeter;
- ka MPV, ka mea e ana i ko lakou nui, a nolaila ko lakou leo, ua ana ia ma femtoliters (kahi metric o ka leo like me 10-15% lita). He mea maʻamau MPV is ma waena o 6 a me 10 femtoliters.
Pono ʻoe e ʻike ʻoi aku ka ikaika o nā platelets me ka leo kiʻekiʻe. ʻO ka mea hope loa, me ka ʻole o ka pathology, e kāohi ʻia ka nui o nā platelets, a me ka nui o ka platelet volume (MPV) no laila e piʻi aʻe i ka wā e hoʻemi ʻia ai ka nui o nā platelets.
No ke aha ka nui o ka platelet mean (MPV) hoao?
Hiki ke hoʻopili ʻia ka nui o ka platelet ma muli o kekahi mau pathologies platelet. A ʻo ia, ʻo ia hoʻi, ka maikaʻi o nā platelets hiki ke hoʻololi ʻia i ka wā o ke ʻano MPV.
I ka wā o ka thrombocytopenia, a no laila ka emi ʻana o ka nui o nā platelets, pono paha ke nānā ʻana i ka MPV, a me ka thrombocytosis (hoʻonui ʻia ka helu platelet) a i ʻole nā thrombopathies ʻē aʻe (nā maʻi no ka nui o nā platelets maʻamau akā. hewa ka hana ana).
ka MPV Ua pili pū kekahi me ka pilikia o ka naʻau, kahi i hoʻohana liʻiliʻi ʻia ma ka hoʻomaʻamaʻa, no ka mea, aia nā pilikia ʻenehana e hoʻopilikia ana i nā ana. ʻO ka ʻoiaʻiʻo, inā loaʻa kahi pilikia cardiovascular a i ʻole kahi pilikia o ka thrombosis, e like me ka phlebitis, hiki ke hoʻopili ʻia kēia me kahi kiʻekiʻe. MPV.
Ma kēia manaʻo, he nui nā hana noiʻi i hana ʻia i loko o nā makahiki he iwakālua i hala e ʻōlelo nei he mea hoihoi ka MPV e hāʻawi i ka ʻike koʻikoʻi i ka hoʻomohala ʻana a me ka wānana e pili ana i nā ʻano maʻi ʻeha.
No laila, hōʻike kēia noiʻi ʻana a kiʻekiʻe MPV ʻike ʻia i ka hui pū ʻana me nā pathology he nui:
- Nā maʻi Cardiovascular;
- Hahau;
- Nā maʻi hanu;
- Kōpaʻa kīnā ʻole;
- Nā maʻi palahēhē;
- Nā maʻi Rheumatoid;
- Diabetes;
- Nā maʻi ʻaʻai ʻokoʻa.
Kūkākūkā, a Ua emi iho ka MPV hiki ke nānā ʻia i nā hihia aʻe:
- Tuberculosis, i ka wā exacerbation o ka maʻi;
- Ulcerative colitis;
- ʻO ka lupus erythematosus ʻōnaehana i nā mākua;
- Nā maʻi neoplastic ʻokoʻa (hoʻomohala ʻole a me ka hoʻonui ʻana o nā hunaola).
ʻO kēia ke kumu, mai kahi ʻano lapaʻau, he mea hoihoi ia e hoʻokumu i nā waiwai paepae o MPV hiki ke hōʻike, ma waena o nā mea ʻē aʻe, i ka ikaika o kahi kaʻina hana inflammatory, ka hele ʻana o kahi maʻi, ka piʻi nui o ka hoʻomohala ʻana i ka maʻi, ka piʻi ʻana o ka pilikia o ka thrombotic complications, ka piʻi nui o ka make a, ka hopena, ka pane o ka mea maʻi i nā lāʻau lapaʻau. pili. Eia nō naʻe, i ka hana lapaʻau, kēia mau hoʻohana o MPV ua kaupalena ʻia a pono e noiʻi hou aku.
Pehea e hana ʻia ai kahi loiloi MPV?
A hoʻāʻo koko maʻalahi Pono ia no ka nānā ʻana i ka nui o ka platelet mean. Pela, ka MPV ana maʻamau i ka wā o ka nānā pinepine ʻana: ʻo ka helu koko (a i ʻole CBC), kahi nānā piha o ke koko e hiki ai ke helu pono i kona mau mea āpau (nā koko ʻulaʻula, nā koko keʻokeʻo a me nā platelets). I ka hoʻomaʻamaʻa, pono e lawe i ke koko ma kahi ʻōpū ʻole.
ka MPV ʻO ka nānā ʻana, i lawe ʻia ma nā paipu i lawe ʻia i ka wā o ka hoʻāʻo ʻana i ke koko, e hana ʻia ma o ke ʻano hana automated, i hoʻohana ʻia mai ka makahiki 1970, a kapa ʻia ma ka ʻōlelo Pelekania "light scattering":
- ʻO ke kumu o kēia hoʻokolokolo ʻana e hoʻomālamalama i nā hunaola me kahi kukuna a i ʻole ke kukui tungsten;
- ʻO ke kukui i pāhola ʻia e kēlā me kēia cell e paʻa ʻia e ka photodetector, a laila hoʻohuli ʻia i loko o ka uila.
- Pēlā, e hiki i ka mea nāna ke kālailai ke helu i ka nui o ka helu o nā pālākiō e hoʻopuni ʻia ma ke kaʻa ʻana iā lākou ma kahi kaola;
- Ka helu ʻana i ka nui o ka platelet mean, MPV, ua hoʻokō ʻia ma o ka hoʻololi logarithmic o ka puʻupuʻu puʻupuʻu platelet.
He aha nā hopena a pehea e wehewehe ai i kahi kiʻekiʻe a haʻahaʻa paha MPV?
E wehewehe i ka hopena o ka hopena o ka nui o ka platelet, pono mau ʻoe ma mua ua nānā mua i ka helu platelet e pili ana me MPV. Hiki ke hoʻemi ʻia kēia helu o nā platelet i ka hanana o thrombositopenia, a i ʻole ma ka ʻaoʻao ʻē aʻe i hoʻonui ʻia i ka hanana o thrombositosis.
- Un MPV kiʻekiʻe ʻo ia hoʻi ke hoʻolaha nei ka nui o nā platelet nui i ke koko;
- Un kahua MPV ʻo ka ʻaoʻao ʻē aʻe, he ʻano nui ko ka platelet liʻiliʻi o ke kanaka.
Pono e kālailai mau ʻia nā hopena ma ka hoʻopili ʻana me ka ʻikepili o ke keʻena lapaʻau, akā me nā hopena ʻē aʻe o ka helu o ke koko. ʻO ka manawa pinepine, nā hopena ʻokoʻa e koi i nā hoʻokolohua hou aʻe.
Hoʻohui ʻia, ma lalo o kekahi mau ʻano, hiki i nā platelet ke hui pū. Aia lākou i kahi liʻiliʻi a ʻike paha e hoʻonui ʻia i ka nui: pono e lawe i kahi laʻana e nānā pono i nā platelet ma lalo o kahi microscope.
Hope loa:
- ʻOiai a hōʻino ʻia ka iwi iwi ʻAʻole hiki ke hoʻokuʻu ʻia inā he ʻano like ʻole MPV, nā kumu pili ʻole i ka iwi iwi he mea maʻamau nō hoʻi: nā maʻi kuni ou maʻi maʻi autoimmune ke luku nei i nā platelet;
- He thrombocytopenia haʻahaʻa (haʻahaʻa ma mua o ka helu maʻamau o nā platelets) pili me kahi haʻahaʻa MPV pili i ka hoʻopau ʻana i ka hana ʻana o nā cell e ka momona: hiki ke lilo i nīnau noanemia. He haʻahaʻa MPV pili pū me ka hoʻopaʻa ʻana splenic (i ka spleen) ʻoiai ʻo ia ka manawa o nā platelet nui loa i hoʻopiʻi ʻia;
- I loko o ke kanaka me ka mōʻaukala ʻole o ke koko ma mua, a me ka helu maʻamau o nā platelets, he mea maʻamau MPV ʻoi aku ka liʻiliʻi o ka pono lapaʻau. No laila ka MPV hiki ke hoʻololi wale mai ala physiological, a me ka loaʻa ʻole o kahi loulou me nā ʻano pilikino.