ʻO ke kumu maʻamau loa oholo pono kīnā ʻole ʻo ka maʻi maʻi diabetes, inā ʻo ka ʻano 1 a i ʻole ke ʻano 2. ʻO kēia no ka mea e hōʻino ana ka maʻi diabetes i nā aʻa koko liʻiliʻi, me nā mea i loko o nā puʻupaʻa. Ma keʻano laulā, ʻo nā maʻi e hoʻopilikia ai i ka maʻi cardiovascular kekahi mau mea pilikia no ka maʻi kīkī. ʻO ka ʻelemakule, ke koko kiʻekiʻe, ka momona, ka maʻi diabetes, ka puhi ʻana a me ka haʻahaʻa HDL cholesterol ("kolesterol maikaʻi")¹. Hiki i nā kumu pilikia ʻē aʻe ke kumu i ka maʻi maʻi maʻi maʻi, e like me kēia:

• Pyelonephritis (ka maʻi o nā puʻupaʻa);
• ʻO ka maʻi maʻi maʻi polycystic;
• ʻO nā maʻi autoimmune, e like me ka systemic lupus erythematosus;

• 'Obstruction o ka mimi (e like me ka prostate ho'onui);
• ʻO ka hoʻohana ʻana i nā lāʻau lapaʻau i hoʻololi ʻia e nā puʻupaʻa, e like me kekahi mau lāʻau lapaʻau chemotherapy.