ʻO ka huaʻōlelo SIBO ke kū nei no ka "liʻiliʻi liʻiliʻi bacterial overgrowth" a e pili ana i ka ulu ʻana o ka maʻi bacterial o ka ʻōpū liʻiliʻi, kahi i hōʻike ʻia e ka nui o nā hua bacteria ma kēia ʻāpana o ka ʻōpū a me ka malabsorption. ʻO nā hōʻike lapaʻau maʻamau ka maʻi maʻi, ke kinoea a me nā hōʻailona o ka malabsorption. ʻO nā kumu e predisposing i ka ulu nui ʻana o ka maʻi bacteria he anatomical (diverticulosis, blind loop, etc.) a i ʻole ka hana (nā pilikia i ka motility intestinal, ka nele o ka huna ʻana o ka ʻōpū o ka ʻōpū). ʻO ka lāʻau lapaʻau ka meaʻai momona momona, haʻahaʻa-carbohydrate, hoʻokele i nā hemahema, lāʻau antibiotic ākea ākea, a me ka hoʻopau ʻana i nā mea kōkua e pale i ka hoʻi hou ʻana.

ʻO ka huaʻōlelo SIBO ke kū nei no ka "liʻiliʻi liʻiliʻi bacterial ulu" a i ʻole ka nui o ka maʻi bacteria o ka ʻōpū liʻiliʻi. Hoʻohālikelike ʻia ia e ka nui o nā bacteria i loko o ka ʻōpū liʻiliʻi (> 105 / ml) i hiki ai ke hōʻeha i nā maʻi malabsorption, ʻo ia hoʻi ka lawa ʻole o ka lawe ʻana o nā meaʻai.

Ma lalo o nā kūlana maʻamau, ʻoi aku ka liʻiliʻi o ka ʻāpana kokoke o ka ʻōpū liʻiliʻi ma mua o 105 bacteria / ml, ka nui o ka aerobic Gram-positive bacteria. Mālama ʻia kēia haʻahaʻa haʻahaʻa bacteria e:

• ka hopena o ka hoʻopaʻa ʻana o ka ʻōpū maʻamau (a i ʻole peristalsis);
• maʻamau ka ʻakika ʻōpū;
• ʻūhū;
• nā immunoglobulins huna A;
• he kiwikā ileocecal e holo nei.

I ka hihia o ka nui o ka maʻi bacteria, ʻoi aku ka nui o ka bacteria,> 105 / ml, loaʻa i ka ʻōpū proximal. Hiki ke hoʻopili ʻia kēia me:

• nā mea ʻino a i ʻole nā ​​loli anatomical i loko o ka ʻōpū a me / a i ʻole ka ʻōpū liʻiliʻi (diverticulosis o ka ʻōpū liʻiliʻi, nā puka puka makapō, nā kūlana post-gastrectomy, strictures a i ʻole ʻāpana obstructions) e hoʻoikaika i ka lohi o ka ʻōpū, e alakaʻi ana i ka ulu nui ʻana o ka bacteria; 
• nā maʻi kaʻa o ka ʻāpana digestive e pili ana me ka neuropathy diabetic, scleroderma, amyloidosis, hypothyroidism a i ʻole idiopathic intestinal pseudo-obstruction e hiki ke hoʻemi i ka haʻalele ʻana i ka maʻi bacteria;
• ʻaʻole i loaʻa kahi huna o ka ʻōpū o ka ʻōpū (achlorhydria), no ka lāʻau lapaʻau a i ʻole ka hoʻomaka ʻana.

ʻO nā ʻano bacteria maʻamau no ka ulu nui ʻana o ka maʻi bacteria i loko o ka ʻōpū liʻiliʻi penei:

• Streptococcus sp ;
• Bacteroides sp ;
• Escherichia coli ;
• Staphylococcus sp;
• Klebsiella sp ;
• a me Lactobacillus.

ʻO kēia mau hua bacteria keu e hoʻemi i ka hiki o ka absorption o nā cell intestinal a hoʻopau i nā meaʻai, e komo pū ana me nā carbohydrates a me ka huaʻa B12, hiki ke hopena i ka malabsorption carbohydrate a me nā meaʻai a me nā huaʻai. Eia kekahi, hana pū kēia mau bacteria i nā paʻakai bile ma ka hoʻololi ʻana iā lākou, pale lākou i ka hoʻokumu ʻana o nā micelles e alakaʻi ai i ka malabsorption o nā lipids. ʻO ka ulu nui ʻana o ka maʻi bacteria e alakaʻi i nā ʻeha o ka mucosa intestinal. 

ʻAʻohe hōʻailona o nā maʻi he nui. Ma waho aʻe o ka pohō kaumaha a i ʻole nā ​​hemahema o nā meaʻai a me nā huaora momona (ʻoi aku ka nui o nā huaora A a me D), ʻo nā hōʻailona maʻamau ka:

• hōʻoluʻolu o ka ʻōpū;
• ʻoi aku ka nui a emi ʻole paha o ka maʻi maʻi;
• steatorrhea, ʻo ia hoʻi, he nui kiʻekiʻe ʻole o nā lipid i loko o ka pahu, i hopena ʻia mai ka malabsorption o nā lipid a me ka hōʻino ʻana i nā membrane mucous;
• ʻōhūhū;
• kinoea kiʻekiʻe, hoʻokumu ʻia e nā kinoea i hana ʻia e ka fermentation o nā carbohydrates.

Pono e hoʻokomo ʻia ka lāʻau antibiotic, ʻaʻole no ka hoʻopau ʻana i ka flora bacteria akā e hoʻololi iā ia i mea e loaʻa ai ka hoʻomaikaʻi ʻana i nā hōʻailona. Ma muli o ke ʻano polymicrobial o ka flora intestinal, pono nā lāʻau lapaʻau ākea ākea e uhi i nā bacteria aerobic a me anaerobic.

No laila, ʻo ka mālama ʻana i ka SIBO e pili ana i ka lawe ʻana, no 10 a 14 mau lā, ma ka waha, hoʻokahi a ʻelua paha o kēia mau lāʻau antibiotic:

• Amoxicillin / clavulanic acid 500 mg 3 mau manawa / lā;
• Cephalexin 250 mg 4 manawa / lā;
• Trimethoprim / sulfamethoxazole 160 mg / 800 mg ʻelua / lā;
• Metronidazole 250 a 500 mg 3 a 4 mau manawa / lā;
• ʻO Rifaximin 550 mg 3 manawa i ka lā.

Hiki ke hoʻololi ʻia kēia lāʻau antibiotic ākea ākea, inā e ʻike hou ʻia nā hōʻailona.

I ka manawa like, pono e hoʻopau ʻia nā kumu e makemake ai i ka ulu nui ʻana o ka bacteria (anatomical and functional abnormalities) a hoʻololi ʻia ka meaʻai. ʻOiaʻiʻo, ʻo ka nui o nā koʻohune i metabolize loa i nā carbohydrates i loko o ka ʻōpū o ka ʻōpū ma mua o nā lipid, kahi papaʻai i kiʻekiʻe i ka momona a haʻahaʻa i ka fiber a me ka carbohydrate - manuahi lactose - paipai ʻia. Pono e hoʻoponopono ʻia nā hemahema o ka huaora, ʻoi aku ka nui o ka huaora B12.