I kekahi mau kāne, hiki ke wehewehe ʻia nā hōʻailona like ʻole e ka emi ʻana o ka hana testosterone.³. No ka manawa, ʻo ka poʻe i ʻike maopopo loa i pili i ka ka nui o nā testosterone ʻo ia nā hōʻailona 3¹¹  :

• Ka emi ʻana o ka makemake moe kolohe;
• ʻAʻole pinepine i ke kūkulu kakahiaka;
• ʻO ka hiki ʻole ke kūkulu ʻia a mālama pono i ka wā o ka moe.

ʻO nā hōʻailona ʻē aʻe e pili pinepine me ka andropause:

• Wela;
• ʻO kahi hāʻule nui o ka ikehu a me ka luhi;
• He nalu o ke kaumaha;
• ʻOmmoe ʻole;
• ʻO nā pilikia liʻiliʻi me ka hoʻomanaʻo a me ka noʻonoʻo;
• ʻO ka pilikia kino nui, nele i ka ikaika kino;
• ʻO ka hoʻonui ʻana i ka momona visceral (abdominal).