ka nā transaminases ua e aia i loko aeea, ʻoi aku hoʻi i loko o ke ake a me nā ʻiʻo. Hoʻopili lākou i ka nui o nā hopena biological.

ʻElua ʻano o nā transaminase:

• ka AST (aspartate aminotransferases), loaʻa nui i loko o ke ake, nā ʻiʻo, ka puʻuwai, nā puʻupaʻa, ka lolo a me ka pancreas
• ka ALT (alanine aminotransferases), pili pili i ke ake

Ua koho mua ʻia nā ASAT e ka acronym TGO (a i ʻole SGOT no serum-glutamyl-oxaloacetate-transferase); ʻO nā ALAT ma lalo o ka acronym TGP (a i ʻole SGPT no ka serum-glutamyl-pyruvate-transaminase).

Hoʻohana ʻia ka hoʻāʻo ʻana o kēia mau enzyme no ka ʻike ʻana i kahi pilikia me ke akepaʻa: ʻo ko lākou hoʻonui ʻana i ke koko ma muli o ka hoʻokuʻu ʻia ʻana e nā pūnaʻi ate poino, no ka laʻana ma muli o kahi he pīpī, Ma ka waiʻona a i ʻole ka lāʻau ʻawaʻawa, Etc.

No laila, hiki i ke kauka ke kuhikuhi i ka lāʻau lapaʻau inā loaʻa nā hōʻailona maʻamau e like me ka luhi, maule, nausea, jaundice (jaundice), a pēlā aku.

• ka pilikia o ka hepatitis B a i ʻole C,
• ka hoʻohana ʻana i ka lāʻau lapaʻau intravenous,
• loao
• diabetes,
• nā maʻi autoimmune,
• a i ʻole ka ʻohana predisposition i ka maʻi ate.

Hana ʻia ka dosage ma kahi laʻana koko maʻalahi, lawe pinepine ʻia ma ka piko o ka kuʻekuʻe. ʻAʻole koi ʻia nā kūlana kūikawā no kēia laʻana (akā ʻo nā hoʻokolohua ʻē aʻe i noi ʻia ma ka hōʻike like e koi iā ʻoe e hoʻokē ʻai, no ka laʻana).

E hoʻokō ʻia ka hoʻoholo ʻana o nā transaminases ʻelua, a e helu ʻia ka ratio ASAT / ALAT, no ka mea e hāʻawi ana i nā hōʻailona i ke ʻano o ka lesion a i ʻole ka maʻi ate.

Inā loaʻa nā hopena kūpono ʻole, e noi ʻia kahi hoʻokolohua lua e hōʻoia i nā waiwai.

Ke kiʻekiʻe ke kiʻekiʻe o ka ASAT a me ka ALT, he hōʻailona maʻamau kēia o ka pōʻino o ka ate.

Eia nō naʻe, ʻaʻole hiki ke hele pū ʻia kekahi mau maʻi, e like me ka maʻi hepaʻa i hoʻokumu ʻia e ka methotrexate a i ʻole ka maʻi hepa C.

ʻO ke kiʻekiʻe o ke kiʻekiʻe o nā transaminases e hāʻawi pinepine i ke kauka i nā hōʻailona maikaʻi e pili ana i ka maʻi:

• A piʻi iki (ma lalo o 2 a 3 mau manawa o ka maʻamau) i ka haʻahaʻa (3 a 10 mau manawa o ka maʻamau) ʻike ʻia i ka maʻi o ka ate pili i ka waiʻona, ka maʻi hepatitis viral mau, a i ʻole steatosis (ka hoʻonui ʻana o ka momona i loko o nā cell ate), no ka laʻana. Ma ka ʻaoʻao ʻē aʻe, ʻoi aku ka manaʻo o kahi ratio ASAT / ALAT> 2 i ka maʻi ate ʻona.
• A kiʻekiʻe kiʻekiʻe (ʻoi aku ma mua o 10 a 20 mau manawa o ka maʻamau) pili i ka hepatitis viral acute (hiki ke piʻi nui i loko o 4 a 6 mau pule ma hope o ka hoʻohaumia ʻana), i nā ʻeha i hoʻoulu ʻia e nā lāʻau lapaʻau a i ʻole ka ona, a me ka "hepatic ischemia ka hāʻawi koko i ke ake).

Hiki i ke kauka ke kauoha i nā ho'āʻo a i ʻole nā ​​hoʻokolohua ʻē aʻe e hōʻoia i ka hōʻoia (e like me ka biopsy ate, no ka laʻana). ʻO ka lāʻau i hoʻomaka ʻia e pili ana i ka maʻi i nīnau ʻia.