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No ke aha e ʻoi aku ka maikaʻi o nā keiki me COVID-19 ma mua o nā pākeke? Ua nīnau kēia nīnau i nā kauka a me nā ʻepekema iā lākou iho mai ka hoʻomaka ʻana o ka maʻi maʻi coronavirus. Ua hoʻolaha nā mea noiʻi ma ke Kulanui ʻo Stanford ma US ua loaʻa iā lākou kahi pane kūpono. Ua paʻi ʻia kā lākou ʻike e ka puke moʻolelo ʻepekema hanohano "Science".
- Hiki i nā keiki o nā makahiki āpau ke loaʻa iā COVID-19, akā ʻo ka hapa maʻamau he mau hōʻailona maʻalahi a ʻaʻohe hōʻailona
- E aʻo: ʻo ke koko i hōʻiliʻili ʻia mai nā keiki ma mua o ka maʻi maʻi i ʻoi aku ka nui o nā cell B i hiki ke hoʻopaʻa iā SARS-CoV-2 ma mua o ke koko makua. ʻOiai ʻaʻole i ʻike ʻia nā keiki i kēia coronavirus
- Manaʻo ka poʻe noiʻi ʻo ka ʻike mua ʻana i ka coronavirus kanaka (ʻo ia ke kumu o ke anu) hiki ke hoʻoulu i ka cross-immunity, a ʻo kēia mau ʻano o ka clonal reactions ke kiʻekiʻe loa i ka wā kamaliʻi.
- Hiki ke loaʻa ka ʻike hou aku e pili ana i ka coronavirus ma ka ʻaoʻao home TvoiLokony
I ka hoʻomaka ʻana o ka maʻi maʻi SARS-CoV-2, ua ʻike ʻia he maʻi maʻalahi nā keiki me ka coronavirus - ʻaʻole pinepine nā hōʻailona o COVID-19 a i ʻole nā hōʻailona maʻalahi.
He mea pono ke kuhikuhi maanei i ka ʻike e pili ana i nā hihia koʻikoʻi pinepine o COVID-19 i waena o nā keiki. - He ʻoiaʻiʻo ka nui o nā poʻe i ka hui o nā keiki a me nā ʻōpio i loaʻa kekahi mau hōʻailona ma hope o ka loaʻa ʻana o ka maʻi coronavirus SARS-CoV-2. Eia nō naʻe, ʻaʻole ia he ʻoiaʻiʻo a ʻaʻole wau i ʻike i loko o koʻu haukapila ke ulu wikiwiki nei nā papa COVID-19 koʻikoʻi i kēia pūʻulu makahiki - wahi a Prof. Magdalena Marczyńska, loea i nā maʻi infectious i nā keiki. Ua hoʻoikaika ke kauka i ka hapa nui o nā keiki i ka maʻi maʻi me ka SARS-CoV-2 coronavirus.
Ke kuhikuhi nei ka Mayo Clinic hanohano i kēia ma kāna kamaʻilio (hana ka hui i ka noiʻi a me nā hana lapaʻau, a me ka mālama maʻi hoʻohui). Ke hōʻike nei ʻo ia ma mayoclinic.org, hiki i nā keiki o nā makahiki āpau ke hoʻomohala i ka COVID-19, akā ʻo ka hapa nui he mau hōʻailona maʻalahi a ʻaʻohe hōʻailona.
- Pehea e loaʻa ai i nā keiki ka COVID-19 a he aha kā lākou mau hōʻailona?
No ke aha kēia hana? Ke hoʻāʻo nei nā ʻepekema e wehe i ka mea pohihihi mai ka hoʻomaka ʻana o ka maʻi maʻi. Ua ʻike ʻia ka wehewehe ʻana e nā ʻepekema mai ke Kulanui ʻo Stanford ʻAmelika. Ua hoʻolaha ʻia lākou ma ka lā 12 ʻApelila ma Science, kekahi o nā nūpepa ʻepekema kaulana loa. Hōʻike nā mea kākau i kēia mau haʻawina i ko lākou wā mua, akā hiki ke wehewehe i ke kumu o ka hoʻololi COVID-19 i nā keiki.
No ke aha i ʻoi aku ka maikaʻi o nā keiki me COVID-19?
I kā lākou ʻimi ʻana i ka pane i ka nīnau ma luna, ua nānā pono nā ʻepekema i ka ʻōnaehana immune. A, ʻoiaʻiʻo, ua loaʻa iā lākou kahi mea e hiki ke kuleana (ma ka liʻiliʻi loa) no ka papa māmā o COVID-19 i nā keiki. Aka, mai kinohi mai.
Aia i loko o ka ʻōnaehana pale: nā cell e like me B lymphocytes (ʻike i ka "ʻenemi", hoʻopuka i nā antibodies), T lymphocytes (ʻike a hoʻopau i nā cell i hoʻopili ʻia i ka maʻi virus) a me nā macrophages (hoʻopau i nā microorganism a me nā mea ʻē aʻe). Eia naʻe, ʻike ka poʻe ʻepekema ʻaʻole kēia manaʻo ua loaʻa iā mākou nā pūʻulu like o nā cell immune. "ʻO nā lymphocytes B ke kuleana no ka hoʻomanaʻo ʻana i nā pathogens i loaʻa i ko mākou kino ma mua, no laila hiki iā lākou ke hoʻomaopopo iā ʻoe inā e ʻike hou lākou iā lākou. Ma muli o ke ʻano o nā maʻi i ʻike mua ʻia a pehea e hoʻololi ai nā mea hoʻokipa e mālama ai i kēia >> hoʻomanaʻo << a hoʻololi a hoʻololi ʻia, loaʻa i kēlā me kēia o mākou he ʻokoʻa >> ʻano << o nā cell immune "- wehewehe nā ʻepekema.
- Lymphocytes - ke kuleana i loko o ke kino a me nā haʻalele ʻana mai ka maʻamau [EXPLAINED]
E hoʻomanaʻo i ka hana ʻana o ka mea hoʻokipa e nā antibodies (immunoglobulins) i loaʻa ma ka ʻili o ka B lymphocyte. Hiki iā lākou ke hoʻopaʻa i kahi antigen / pathogen i hāʻawi ʻia (ʻike kēlā me kēia antibody i hoʻokahi antigen kikoʻī), e hoʻoulu ai i kahi pane kūlohelohe e kūʻē iā ia (kahi ʻano o nā hopena pale).
Me kēia mau mea a pau, ua kālailai nā mea noiʻi ma ke Kulanui ʻo Stanford i ka ʻokoʻa o nā cell immune mai kēlā me kēia kanaka, akā pehea e loli ai lākou i ke ola o ke kanaka. Ua ʻike lākou i ke koko i hōʻiliʻili ʻia mai nā keiki ma mua o ka maʻi maʻi i loaʻa i nā cell B ʻoi aku ka hiki ke hoʻopaʻa iā SARS-CoV-2 ma mua o ke koko o nā pākeke. Ua hana ʻia kēia ʻoiai ʻaʻole i ʻike ʻia nā keiki i kēia pathogen. Pehea e hiki ai?
COVID-19 i nā keiki. Pehea ka hana ʻana o kā lākou ʻōnaehana pale?
Ua wehewehe ka poʻe noiʻi e kūkulu ʻia nā mea loaʻa i ʻōlelo ʻia ma luna o ka 'iwi kuamoʻo' i ʻike ʻia he immunoglobulin sequences. Eia nō naʻe, hiki iā lākou ke hoʻololi a hoʻololi paha, e hana ana i kahi ʻano āpau o nā mea hoʻokipa hiki ke luku i nā pathogens i hana ʻole ʻia e ke kino. Hoʻopā mākou ma ʻaneʻi i ka manaʻo o ka mea i kapa ʻia ke kūʻē kea. Mahalo i ka hoʻomanaʻo ʻana i nā lymphocytes, ʻoi aku ka wikiwiki a me ka ikaika o ka pane ʻana o ka immune ma ka hui hou ʻana me ka antigen. Inā loaʻa kēlā pane i ka hihia o ka maʻi me kahi pathogen like, ʻo ia ka cross-resistance.
ʻO ka ʻoiaʻiʻo, i ka nānā ʻana o nā kānaka ʻepekema i ka B-cell receptors i nā keiki, ua ʻike lākou, ke hoʻohālikelike ʻia me nā pākeke, ua ʻoi aku ka nui o nā 'clones' e kuhikuhi ana i nā maʻi maʻi a me nā bacteria a lākou i hoʻopili ai. Ua ʻike hou ʻia nā cell B hou i loko o nā keiki, a hiki iā lākou ke 'hoʻololi' e lilo i mea kūpono e kūʻē iā SARS-CoV-2 me ka ʻole o ka hoʻopili mua ʻana me ia.
Wahi a ka poʻe noiʻi, ʻoi aku paha kēia ma muli o ka ʻoi aku ka maikaʻi o ka neʻe ʻana o ka ʻōnaehana pale o nā keiki i kahi ākea o nā antigens ma hope o ka ʻike ʻana i kahi coronavirus ʻē aʻe, ʻoi aku ka pōʻino ma mua o ka mea nona ka maʻi maʻi o kēia manawa (e hoʻomanaʻo ʻo nā coronaviruses ke kuleana. no kahi o 10-20 pakeneka o ke anu). 'Ke manaʻo nei mākou e hiki i ka ʻike mua ʻana i ka coronavirus kanaka ke hoʻoulu i ka cross-immunity a ʻo ia mau pane clonal e pinepine pinepine ʻia i ka wā kamaliʻi,' i hoʻopau ai nā mea noiʻi, me ka ʻōlelo ʻana he mea koʻikoʻi ka pane ʻana i nā keiki i ka wā e hoʻokumu ai lākou i ka puna mua o ka hoʻomanaʻo. ʻO nā lymphocytes B, ka mea i hoʻohālikelike i nā pane pale o ke kino e hiki mai ana ».
ʻO ka mea hope loa, hōʻike nā mea noiʻi ma ke Kulanui ʻo Stanford aia kekahi mau mea e hoʻomāhuahua ai nā keiki i nā hōʻailona COVID-19. ʻO kā lākou mau ʻike, ua wehe ʻia kekahi o nā mea pohihihi, e hāʻawi ana i ka ʻike i ka loli B-cell o ka wā kamaliʻi a me kāna kuleana i nā pane kūlohelohe e hiki mai ana.
Hiki paha iā ʻoe ke hoihoi iā:
- ʻOi aku ka paʻakikī o nā keiki i ka COVID-19. ʻO kekahi hōʻailona koʻikoʻi loa
- Hiki i ka COVID-19 ke hana i nā pilikia thyroid
- ʻOi aku ka nui o nā wahine hāpai i ka maʻi. He aha ka mea e maʻi ai ka wahine hāpai me COVID-19?
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