ʻO ka meaʻai paʻakai, he mea maʻamau ka pōʻino i ke olakino, i loko o nā hiʻohiʻona tumo murine e kāohi i ka ulu ʻana o ka maʻi maʻi no ka mea e hoʻoulu i ka hana o ka ʻōnaehana pale, hōʻike i ka puke pai Frontiers in Immunology. E hoʻohana ʻia ka noiʻi i ka wā e hiki mai ana?
ʻO ka ʻai ʻana i ka paʻakai kiʻekiʻe he kumu pilikia ia no ke koko kiʻekiʻe a me ka maʻi cardiovascular. Ua hōʻike pū ʻia nā haʻawina hou i ka nui o ka paʻakai i ka meaʻai hiki ke hoʻonui i ka aggressiveness o nā cell immune, ka mea e hāpai i nā maʻi autoimmune.
ʻEwalu mau meaʻai i ʻoi aku ka nui o ka paʻakai ma mua o kou manaʻo
Eia nō naʻe, ʻoiai ʻoi aku ka pōʻino o ka ʻōnaehana immune kiʻekiʻe ma mua o ka maikaʻi o ke kino olakino, hiki iā ia ke loaʻa kahi hana kūpono i ka hihia o ka maʻi kanesa.
E like me ka manaʻo o nā noiʻi keʻena hoʻokolohua e pili ana i nā hiʻohiʻona ʻiole, i hana ʻia e kahi hui honua i alakaʻi ʻia e prof. ʻO Markus Kleinewietfeld mai VIB (Flemish Institute of Biotechnology), ʻo ka lawe ʻana i ka paʻakai kiʻekiʻe e pale i ka ulu ʻana o ka maʻi maʻi. ʻIke ʻia ka hopena ma muli o ka hoʻololi ʻana i ka hana ʻana o nā cell myeloid lineage suppression cell (MDSCs), kahi mea nui i ka hakakā ʻana i ke kanesa. Kāohi nā MDSC i ka hana o nā pūnaewele pale ʻē aʻe, akā i loko o kahi paʻakai paʻakai, nāwaliwali ko lākou mau hopena pale a hoʻouka ʻia nā ʻano ʻano ʻē aʻe i ke koko. Ua ʻike pū ʻia kahi hopena like o ke kaiapuni paʻakai ma MDSC i ka wā i hoʻomaʻamaʻa ʻia ai nā cell tumor kanaka.
Wahi a nā mea kākau, hiki i ka noiʻi hou ke hoʻomaikaʻi i nā hopena o ka mālama ʻana i ka maʻi kanesa ma ke ala maʻalahi a maʻalahi loa. Akā ʻo ka mea mua, pono ʻoe e hoʻomaopopo piha i kēia hopena a me nā mīkini molekala kikoʻī. Ua ʻike ʻia ʻo ka lawe ʻana i ka paʻakai kiʻekiʻe e hāpai, no ka laʻana, ka ulu ʻana o ka maʻi maʻi ʻōpū.