ʻO Acanthosis nigricans (AN) kahi ʻano ʻili e ʻike ʻia e nā ʻeleʻele, nā wahi mānoanoa o ka ʻili i hana ʻia, ma ka hulu o ka ʻāʻī a me nā ʻāpana lima. ʻO kēia dermatosis pinepine pinepine i ka benign a pili pū me ka momona, akā hiki ke lilo i hōʻailona o kahi maʻi maʻi e like me kahi tumo malignant.

ʻO ka helehelena o ka pouli, mānoanoa, ʻoʻoleʻa a maloʻo, akā ʻeha ʻole, ʻāpana o ka ʻili kahi ʻano o nā Acigosis nigricans. Nā hualoaʻa kā lākou kala mai ka hyperpigmentation (hoʻonui melanin) a me ka mānoanoa mai hyperkeratosis (hoʻonui keratinization). Hiki i nā ulu ulu like ke ulu. Hiki ke ʻike ʻia kēia mau kiko ma nā ʻāpana āpau o ke kino, akā makemake lākou e hoʻopili i nā pale o ka ʻili, ma ka pae o ka ʻāʻī, nā lima lima, nā ʻūlū a me nā ʻāpana genito-anal. ʻIke iki ʻia lākou ma nā kuli, kuʻekuʻe, nā umauma a me ka piko. Pono e kāohi i kahi kuhi kikoʻī i ke kuhiakau o ka maʻi ʻo Addison [[link]] nāna e like nā hana.

Manaʻo nā kānaka noiʻi he acanthosis nigricans kahi hopena o ke kūpaʻa o ka ʻili i nā kiʻekiʻe kiʻekiʻe o ka insulin, ka hormone i hana ʻia e ka pancreas e hoʻoponopono ana i ka glucose koko. Hiki ke hoʻopili ʻia kēia kūpaʻa o ka insulin me nā ʻano maʻi like ʻole, e like me ka momona a me ka maʻi kōkō ʻelua. I kona ʻano akahai, ka mea maʻamau a ʻike ʻia e like me pseudoacanthosis nigricans, he mau ʻili ia o ka ʻili e pili ana i ka momona a hoʻihoʻi ʻia me ka pohō kaumaha. Hiki i nā lāʻau ke kumu o kekahi mau hihia, e like me ka ulu ʻana o ka hormones a i ʻole nā ​​kaohi haʻi.

Hiki i nā Acigosis nigricans ke lilo i hōʻailona waho a ʻike ʻia o kahi maʻi kūmau, hāmau. ʻOi aku ka maikaʻi o kēia ʻano malignant no ka mea ʻo ka maʻi ʻino i hoʻohuli pinepine ʻia he tumo huhū: ʻike ʻia ia ma 1 i 6 mau maʻi me ka maʻi ʻaʻai, e pili pinepine ana i ka ʻōnaehana gastrointestinal a i ʻole ka ʻōnaehana genitourinary. -keaola. ʻO ka awelika o ke ola o ka mea maʻi me ka maʻi maʻi AN i hoʻemi ʻia i kekahi mau makahiki. (000)

ʻO nā kāne a me nā wahine e hopohopo like a nā nigricans acanthosis hiki ke ʻike ʻia i nā makahiki, akā ʻoi aku ka maikaʻi i ka wā makua. Hoʻomaopopo e pili pinepine ka poʻe ʻili ʻeleʻele, no laila, ʻo ka prevalence o NA he 1-5% ma waena o nā keʻokeʻo a me 13% i waena o nā ʻeleʻele. (1) ʻIke ʻia kēia hōʻike ʻili ma kahi o ka hapalua o nā mākua me ka momona nui.

ʻAʻole lele ka maʻi. Aia kekahi mau hihia ʻohana o AN, me ka autosomal domant transmission (ke kuhi nei he 50% ka pilikia o ka mea i hoʻopilikia ʻia i ka lawe ʻana i ka maʻi i kā lākou keiki, kaikamahine a me nā keiki kāne).

ʻO ka mālama ʻana no AN māmā me ka hōʻemi ʻana i ka pae o ka insulin i loko o ke koko me ka papaʻai kūpono, ʻoiai ʻo AN ke lilo i hōʻailona hōʻailona no ka maʻi kō. I kēlā me kēia hihia, pono e nīnau i kahi dermatologist i ka hanana o ke ʻano o kahi ʻili o ka ʻeleʻele a me ka manoanoa o ka ʻili. Ke hōʻike ʻia ʻo AN i loko o kahi kanaka ʻaʻohe momona o ke kino, pono e hana i nā hoʻokolokolo āpau e ʻike ʻaʻole pili ia i ke kū ʻana o kahi tumo.