Pepeluali 24, 2012 - ʻOiai hoʻohana nui ʻia, ʻike ʻia nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) e hōʻike i kahi pilikia maoli i ke olakino. Ma waena o nā mea i ʻike nui ʻia ʻo aspirin, Advil®, Antadys®, Ibuprofen® a i ʻole ʻo Voltarene®, nā lāʻau i kuhikuhi pinepine ʻia.

ʻO kēia papa o nā lāʻau anti-inflammatory i manaʻo ʻia he mea hōʻeha paha i ka puʻuwai a me nā puʻupaʻa. ʻOiaʻiʻo, ua kuleana ʻia nā NSAID no:

• mea'ōnaehana mānowai koko kāna hana

I mea e hōʻoluʻolu ai i ka ʻeha, nā lāʻau non-steroidal anti-inflammatory lāʻau ālai i ka hana o ʻelua enzymes (= protein e ʻae ana i kahi hana biochemical) i kapa ʻia ʻo COX-1 a me COX-2.

ʻO ka pale ʻana i ka COX-2 e nā NSAID e pale aku i ke kāpili ʻana o ke koko a me ka synthesis o thromboxanes, nā homone me kahi kuleana vasoconstrictor, no laila e hoʻonui ana i ke kahe o ke koko a me nā pilikia o ka maʻi puʻuwai.

• Ulcer a me ke kahe ʻana o ka maʻi i loko o ka digestive tract

ʻAe ʻo COX-1 i ka hoʻokumu ʻia ʻana o nā prostaglandins, nā metabolites i hana ʻia i ka palapū, ka hakuʻala a me ka puʻuwai. ʻO ka pāpā ʻana o COX-1 e nā lāʻau anti-inflammatory nonsteroidal a laila pale iā ia mai ka pale ʻana i ka digestive tract, a hiki ke kumu i kahi ulcer peptic.

• Hoka kōpaʻa

ʻO kēia kaohi ʻana o COX-1 e hāpai pū kekahi i ka maikaʻi ʻole o ke kōpaʻa ma o ka palena ʻana i ka perfusion o ka puʻupaʻa.

Ma ka laulaha, ʻo ka poʻe ʻelemākule ka mea e hopohopo nui nei i kēia mau pilikia, no ka mea, ke emi nei kā lākou hana hōʻino, kahi paradox, ke ʻike mākou ua kuhikuhi ākea nā lāʻau anti-inflammatory e hōʻoluʻolu i ka ʻeha e pili ana i ka osteoarthritis.

Anaïs Lhôte - PasseportSanté.net

Source: ʻO kāu mau lāʻau, ʻO Philippe moser