ʻO ka maʻi o Charcot, i kapa ʻia ʻo amyotrophic lateral sclerosis (ALS) he maʻi neurodegenerative. Hiki mālie i ka neurons a alakaʻi i ka nāwaliwali o ka ʻiʻo ma hope o ka lolo. He pōkole loa ke ola o nā maʻi. Ma ka ʻōlelo Pelekania, ua kapa ʻia ʻo ia ʻo ka maʻi ʻo Lou Gehrig, no ka hoʻohanohano ʻana i kekahi mea pāʻani kinipopo kaulana i loaʻa i kēia maʻi. ʻO ka inoa "Charcot" mai ka mea neurologist Farani i wehewehe i ka maʻi.

ʻO nā neurons i hoʻopilikia ʻia e ka maʻi o Charcot, he mau neuron motor (a i ʻole motor neurons), ke kuleana o ka hoʻouna ʻana i ka ʻike a me nā kauoha neʻe mai ka lolo a i nā ʻiʻo. E hoʻohaʻahaʻa mālie nā ʻaʻalolo a laila make. ʻAʻole hoʻomalu hou ʻia nā ʻiʻo manawaleʻa e ka lolo a hoʻoulu ʻia. ʻAʻole hana, pau lākou i ka hana ʻole a atrophy. I ka hoomaka ana o keia maʻi neurological holomua, pilikia ka mea i hoʻopilikia ʻia i ka ʻili ʻana o ka ʻiʻo a i ʻole nāwaliwali o nā lālā, nā lima a i ʻole nā ​​wāwae. He pilikia ka ʻōlelo kekahi.

Hoʻokō o neuron motor luna Hōʻike nui ʻia e ka lohi ʻana o nā neʻe (bradykinesia), hoʻemi i ka hoʻonohonoho ʻana a me ka dexterity a me ka ʻoʻoleʻa ʻiʻo me ka spasticity. Hoʻokō o neuron motor haʻahaʻa ʻike nui ʻia ma muli o ka nāwaliwali o ka ʻiʻo, cramps a me ke atrophy o nā ʻiʻo e alakaʻi ana i ka lolo.

Hiki i ka ma'i o Charcot ke pa'akikī i ka ale 'ana a pale i ka 'ai pono 'ana o ka po'e. Hiki i ka poʻe maʻi ke loaʻa i ka ʻai ʻole a i ʻole ke ala hewa (= pili i ka pōʻino i ka ʻai ʻana i nā mea paʻa a i ʻole nā ​​wai ma o ka ʻōpū hanu). Ke holomua ka maʻi, hiki ke hoʻopilikia i nā ʻiʻo e pono ai hāhā.

Ma hope o 3 a 5 mau makahiki o ka ulu ʻana, hiki i ka maʻi o Charcot ke hoʻoulu i ka hanu hanu e hiki ai i ka make. ʻO ka maʻi, e pili ana i nā kāne ma mua o nā wahine (1,5 a 1) hoʻomaka ma kahi o 60 mau makahiki (ma waena o 40 a 70 mau makahiki). ʻAʻole ʻike ʻia kona kumu. Ma hoʻokahi o ka ʻumi mau hihia i manaʻo ʻia he kumu genetic. ʻO ke kumu o ka hoʻomaka ʻana o ka maʻi ma muli o nā kumu like ʻole, ka nohona a me ka genetic.

ʻAʻohe ʻaʻohe lāʻau lapaʻau o ka ma'i o Charcot. ʻO ka lāʻau lapaʻau, riluzole, e hoʻolōʻihi iki i ka holomua o ka maʻi, ʻo kēia evolution e loli loa mai kekahi kanaka a i kekahi a ʻo ia hoʻi, i ka maʻi hoʻokahi, mai kahi manawa a i kekahi. I kekahi, ʻo ka maʻi, ʻaʻole i pili i ka naʻau (ʻike, hoʻopā, lohe, honi, ʻono), hiki ke kūpaʻa i kekahi manawa. Pono ka ALS i ka nānā pono. ʻO ka hoʻoponopono ka mea nui o ka hoʻomaha ʻana i nā hōʻailona o ka maʻi.

Ka laha o keia mai

Wahi a ka hui no ka noiʻi ʻana i ka maʻi o Charcot, ʻo ka nui o ka maʻi o Charcot he 1,5 mau hihia hou i kēlā me kēia makahiki no 100 mau kānaka. Ma kahi kokoke i 1000 nā hihia hou i kēlā me kēia makahiki ma Farani.

ʻO ka hōʻailona o ka maʻi o Charcot

ʻO ka hōʻailona o ALS ke kōkua i ka hoʻokaʻawale ʻana i kēia maʻi mai nā maʻi neurological ʻē aʻe. He mea paʻakikī ia i kekahi manawa, no ka mea ʻaʻohe māka kikoʻī o ka maʻi i loko o ke koko a no ka mea i ka hoʻomaka ʻana o ka maʻi, ʻaʻole maopopo loa nā hōʻailona lapaʻau. E ʻimi ka neurologist i ka ʻoʻoleʻa i loko o nā ʻiʻo a i ʻole nā ​​ʻāʻī.

Hiki i ka hōʻailona ke komo pū kekahi electromyogram, ka hoʻokolokolo e hiki ai ke nānā i ka hana uila i loko o nā ʻiʻo, kahi MRI e nānā i ka lolo a me ke kuamoʻo. Hiki ke kauoha ʻia nā hoʻāʻo ʻana i ke koko a me ka mimi, no ka hoʻoholo ʻana i nā maʻi ʻē aʻe i loaʻa nā hōʻailona maʻamau i ka ALS.

Ka ulu ʻana o kēia maʻi

No laila, hoʻomaka ka maʻi o Charcot me ka nāwaliwali o ka ʻiʻo. ʻO ka pinepine, ʻo nā lima a me nā wāwae ka mea mua. A laila ka ʻiʻo o ke alelo, ka waha, a laila ka hanu.

Nā kumu o ka maʻi o Charcot

E like me ka mea i ʻōlelo ʻia, ʻaʻole ʻike ʻia nā kumu i kēia manawa ma kahi o 9 o 10 mau hihia (5 a 10% o nā hihia he hoʻoilina). Ua ʻimi ʻia kekahi mau ala e wehewehe ai i ke ʻano o ka maʻi: ka maʻi autoimmune, ke kaulike ʻole kemika… No ka manawa me ka kūleʻa ʻole.