ʻO ka allergy protein waiu bipi, a i ʻole APLV, ka maʻi ʻai maʻamau i nā pēpē. ʻIke pinepine ia i nā mahina mua o ke ola. ʻOiai ʻokoʻa loa kēia mau hōʻailona mai kahi keiki a i kekahi, hiki ke paʻakikī kona ʻike i kekahi manawa. Ke hana ʻia ka hōʻailona, ​​​​pono ʻo APLV i kahi meaʻai hoʻopau, ma lalo o ka mākaʻi olakino. ʻO ka allergy me ka wānana maikaʻi, ulu maoli ia i ka ulu ʻana o ka hoʻomanawanui i ka hapa nui o nā keiki.

ʻO ke ʻano o ka waiū bipi

ʻO ka allergy protein waiu bipi, a i ʻole APLV, e pili ana i ka loaʻa ʻana o nā hōʻike lapaʻau ma hope o ka ʻai ʻana i ka waiū bipi a i ʻole nā ​​huahana waiu, ma hope o ka hopena immunological kūʻē i nā protein waiu bipi. Aia ma kahi o kanakolu mau polokina like ʻole i ka waiū bipi, me kekahi:

• lactalbumin,
• β-lactoglobulin,
• serum albumin bipi,
• nā immunoglobulin o nā bipi,
• nā hihia αs1, αs2, β et al.

He mau allergens paha lākou. ʻO nā PLV kekahi o nā allergens nui i nā makahiki 2 mua o ke ola, ʻo ia ka mea maʻalahi mai ka makahiki mua, ʻo ka waiū ka meaʻai nui a ke pēpē. 

ʻO nā pathologies like ʻole

Ma muli o ke ʻano o ka hana, aia nā pathologies like ʻole: 

ʻO ka maʻi maʻi waiu pipi pili i ka IgE (IgE-mediated)

a i ʻole ka APLV ponoʻī. ʻO nā protein i loko o ka waiū bipi e hoʻoulu i kahi pane ʻeha me ka hana ʻana o ka immunoglobulin E (IgE), nā antibodies i hana ʻia e pane i kahi allergen. 

ʻAʻole ka IgE hilinaʻi waiu intolerance

Hoʻopili ke kino me nā hōʻailona like ʻole i ka ʻike ʻana i nā antigens waiū bipi, akā ʻaʻohe hana o IgE. I nā kamaliʻi, ʻo kēia ke ʻano maʻamau. 

Hiki i ka APLV ke hoʻopilikia i ka ulu ʻana o ka pēpē a me ka mineralization iwi no ka mea ʻaʻole komo maikaʻi nā meaʻai.

ʻO nā hōʻike lapaʻau o APLV he loli nui ma muli o ke kumu kumu, ke keiki a me kona mau makahiki. Hoʻopilikia lākou i ka ʻōnaehana digestive, ka ʻili, ka ʻōnaehana hanu. 

I ka hihia o IgE-mediated APLV

I ka IgE-mediated APLV, hiki koke mai nā hopena: ka maʻi waha a me ka luaʻi i ukali ʻia e ka maʻi paʻi, nā hopena maʻamau me ka pruritus, urticaria, angioedema, a i nā hihia koʻikoʻi ʻoi aku ka anaphylaxis.

I ka hihia o IgE unmediated

I ka hihia o IgE unmediated, hoʻopaneʻe pinepine ʻia nā hōʻike: 

• eczema (atopic dermatitis);
• ʻO ka maʻi maʻi a i ʻole ka constipation;
• ka hoʻomau mau ʻana a i ʻole ka luaʻi ʻana;
• kahe koko;
• colic, ʻeha ʻōpū;
• ka pehu a me ke kinoea;
• lawa ʻole ka loaʻa ʻana o ke kaumaha;
• irritability, pilikia hiamoe;
• rhinitis, ma'i ma'i mau;
• nā maʻi pepeiao pinepine;
• hānō pēpē.

He ʻokoʻa loa kēia mau hiʻohiʻona mai kekahi pēpē a i kekahi pēpē. Hiki i ke keiki hoʻokahi ke loaʻa nā hopena koke a lohi. Hoʻololi pū nā hōʻailona me ka makahiki: ma mua o 1 mau makahiki, ʻoi aku ka maʻamau o ka ʻili a me nā hōʻailona digestive. Ma hope iho, hōʻike hou ka APLV iā ia iho e nā hōʻailona ʻili-mucous a me ka hanu. ʻO kēia nā mea a pau e paʻakikī ai ka hōʻoia ʻana o APLV.

Ke alo nei me nā hōʻailona digestive a / a i ʻole ka ʻili i loko o ka pēpē, e hana mua ke kauka i kahi hoʻokolohua lapaʻau a me kahi nīnau e pili ana i nā ʻano maʻi like ʻole, ka ʻai a ke pēpē, kāna ʻano a i ʻole ka moʻolelo ʻohana o ka maʻi maʻi. Ma keʻano kūikawā, hiki i ke kauka ke hoʻohana i ka CoMiSS® (ka helu hōʻailona pili i ka waiū bipi), kahi helu e pili ana i nā hōʻailona nui e pili ana iā APLV. 

ʻO nā hoʻokolohua like ʻole e ʻike i kahi APLV

I kēia lā, ʻaʻohe hoʻāʻo olaola e hiki ke hoʻokumu a hōʻole paha me ka maopopo o kahi hōʻailona o APLV. No laila ua hoʻokumu ʻia ka ʻike ma luna o nā hoʻokolohua like ʻole.

No APLV pili i ka IgE

• he hoao ili waiu bipi. ʻO kēia hoʻāʻo ʻili e pili ana i ka hoʻokomo ʻana i kahi ʻāpana allergen i hoʻomaʻemaʻe ʻia i loko o ka ʻili me kahi lancet liʻiliʻi. Ma hope o 10 a 20 mau minuke, loaʻa ka hopena. Hōʻike ʻia kahi hōʻike maikaʻi e kahi papule, (kahi pimple liʻiliʻi). Hiki ke hana ʻia kēia hoʻāʻo ʻana i nā kamaliʻi, a ʻaʻohe ʻeha.
• he ho'āʻo koko no ka IgE kiko'ī.

No kahi APLV hilinaʻi ʻole i ka IgE

• he ho'āʻo hoʻopaʻa a hoʻopaʻa paha. Hoʻokomo ʻia nā kīʻaha liʻiliʻi i loaʻa ka allergen ma ka ʻili o ke kua. Wehe ʻia lākou ma hope o 48 mau hola, a loaʻa ka hopena ma hope o 24 mau hola. ʻO nā hopena maikaʻi mai kahi erythema maʻalahi a hiki i ka hui pū ʻana o ka erythema, vesicle a me nā ʻōpū. 

Hana ʻia ka hōʻoia ʻana me ka ʻoiaʻiʻo e ka hoʻāʻo kipaku ʻia (ua hoʻopau ʻia nā protein waiu bipi mai ka ʻai ʻana) a me ka hoʻopiʻi waha i nā proteins waiū bipi, me ka nānā ʻole i ke ʻano immunological.

Hoʻokumu ʻia ka hoʻokele ʻana o APLV ma ka hoʻopau loa ʻana i ka allergen. E kuhikuhi ʻia nā waiū kikoʻī i ka pēpē, e like me nā ʻōlelo a ke Kōmike Nutrition o ka French Pediatric Society (CNSFP) a me ka European Society for Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN). 

ʻO ka hoʻohana ʻana i kahi hydrolyzate protein nui (EO)

Ma ka manaʻo mua, e hāʻawi ʻia kahi hydrolyzate nui o nā protein (EO) a i ʻole hydrolyzate kiʻekiʻe o nā protein (HPP) e hāʻawi ʻia i ka pēpē. ʻO kēia mau waiū i hoʻomākaukau ʻia mai ka casein a i ʻole ka whey i ka hapa nui o nā hihia i ʻae maikaʻi ʻia e nā pēpē APLV. Inā hoʻomau nā hōʻailona ma hope o ka hoʻāʻo ʻana i nā ʻano hydrolysates ʻokoʻa, a i ʻole inā loaʻa nā hōʻailona maʻi maʻi koʻikoʻi, e kuhikuhi ʻia kahi ʻano pēpē e pili ana i nā waikawa amino synthetic (FAA). 

ʻO ka hoʻomākaukau ʻana i ka protein waiu soy

ʻOi aku ka maikaʻi o ka hoʻomākaukau ʻana i ka protein Soymilk (PPS). ʻO kēia mau phytochemical i loko o ka soy he phytoestrogens: ma muli o ko lākou molecular like, hiki iā lākou ke hoʻohālike i ka estrogens, a no laila ke hana nei lākou ma ke ʻano he endocrine disruptors. Ua kuhikuhi ʻia lākou ma ke ʻano he kolu o ka laina, ʻoi aku ka maikaʻi ma hope o 6 mau mahina, e hōʻoiaʻiʻo e koho i ka waiū me kahi ʻano isoflavone hoʻemi.

waiu hypoallergenic (HA)

ʻAʻole hōʻike ʻia ka waiū hypoallergenic (HA) i ka hihia o APLV. ʻO kēia waiū, i hana ʻia mai ka waiū bipi, i hoʻololi ʻia i mea e emi ai ka allergenic, ua manaʻo ʻia no ka pale ʻana i nā pēpē me nā allergies (ʻo ia hoʻi ka mōʻaukala ʻohana), ma ka ʻōlelo aʻo olakino, i nā mahina ʻeono mua o ka pēpē. 

ʻO ka hoʻohana ʻana i nā wai huaʻai

ʻO ka hoʻohana ʻana i nā wai huaʻai (soy, raiki, ʻalemona a me nā mea ʻē aʻe) ʻaʻole i hoʻohālikelike ʻia i nā pono meaʻai o nā pēpē. ʻO ka waiū o nā holoholona ʻē aʻe (mare, kao), ʻaʻole lākou e hāʻawi i nā meaʻai āpau e pono ai no ka pēpē, a hiki ke hoʻoulu i nā hopena maʻi ʻē aʻe, ma muli o ka pilikia o ka cross-allergies.

Pono ka ʻai hoʻopau ʻana no ka liʻiliʻi o 6 mau mahina a i ʻole a hiki i ka makahiki 9 a i ʻole 12 a i ʻole 18 mau mahina, ma muli o ke koʻikoʻi o nā hōʻailona. E hana ʻia ka hoʻokomo hou ʻana ma hope o ka hoʻāʻo hoʻokūkū waha (OPT) me ka waiū bipi i hana ʻia ma ka haukapila. 

Loaʻa i ka APLV kahi prognosis maikaʻi e hoʻomaikaʻi i ka holomua holomua o ka ʻōnaehana immune o ke keiki a me ka loaʻa ʻana o ka hoʻomanawanui i nā proteins waiū. I ka hapanui o nā hihia, ʻo ke ʻano kūlohelohe e pili ana i ka hoʻomohala ʻana i ka hoʻomanawanui i nā keiki ma waena o 1 a me 3 mau makahiki: ma kahi o 50% ma ka makahiki o 1 makahiki,> 75% ma ka makahiki 3 a me> 90% i ka makahiki. makahiki o 6.

I nā pēpē i hānai ʻia, he haʻahaʻa loa ka maʻi o APLV (0,5%). ʻO ka hoʻokele ʻana o APLV i kahi pēpē i hānai ʻia ʻo ia ka hoʻopau ʻana i nā huahana waiu a pau mai ka ʻai ʻana o ka makuahine: ka waiū, yogurt, cheese, butter, sour cream, etc. Inā hoʻomaikaʻi a nalowale paha nā hōʻailona, ​​​​hiki i ka makuahine hānai ke hoʻāʻo i ka hoʻokomo hou ʻana o nā protein waiu bipi i kāna ʻai, me ka ʻole o ka nui o ka nui o ka nui i ʻae ʻia e ke keiki.