ʻOi aku ma mua o ʻelima mau makahiki i hala aku nei, ua ʻike nā ʻepekema ʻo ka ʻai ʻana i ka ʻiʻo palai - me nā ʻāpana palai hohonu, ka ʻiʻo i kālua a me ka ʻiʻo barbecued - e hoʻonui nui i ka pilikia o ka maʻi maʻi ʻōpū.
ʻO kēia no ka mea he heterocyclic amines, i ʻike ʻia i loko o ka ʻiʻo i hoʻomaʻamaʻa ʻia, hoʻopau i ka metabolism maʻamau. Eia naʻe, e like me ka noiʻi olakino hou loa, ʻoi aku ka ʻino o ke kūlana me ka ʻiʻo palai ma mua o ka mea i manaʻo mua ʻia.
Ma waho a'e o ka ma'i 'a'ai o ka 'ōpū, 'o ia ho'i ke kumu o ka ma'i ma'i a me ka dementia, 'o ia ho'i, 'ane'ane like ka hopena o ke kino me ka 'ai i ho'oma'ama'a nui 'ia, ka 'ai "kemika" a me ka "wikiwiki", a i 'ole ka 'ai i mo'a hewa 'ia. Manaʻo nā kauka i ka ulu ʻana o nā maʻi koʻikoʻi a hiki ʻole ke hoʻihoʻi ʻia e hoʻonui ʻia me ka nui o ka ʻai ʻana o ke kanaka i ia mau meaʻai - inā paha he burger i hoʻopiha ʻia me nā preservatives mai kahi hale ʻaina a i ʻole kahi steak "kahiko maikaʻi".
Ua alakaʻi ʻia ke aʻo ʻana e ka Icahn School of Medicine ma New York a paʻi ʻia ma ka nūpepa ʻepekema ʻAmelika Proceedings of the National Academy of Sciences. Hōʻike nā hualoaʻa e pili pono ana kēlā me kēia ʻiʻo i palai nui ʻia (inā i ʻai ʻia a i ʻala ʻia paha) me kekahi maʻi koʻikoʻi ʻē aʻe – ka maʻi o Alzheimer.
I loko o kā lākou hōʻike, ua wehewehe kikoʻī nā kauka i ke ʻano o ke ʻano o nā mea i kapa ʻia ʻo AGE i ka wā o ka mālama wela o ka ʻiʻo, "Advanced Glicated End products" (Advanced Glicated End products, or AGE for short - "makahiki"). ʻAʻole aʻo liʻiliʻi kēia mau mea, akā ua maopopo ka poʻe ʻepekema he pōʻino loa lākou i ke kino a ke kumu maoli nei i nā maʻi maʻi koʻikoʻi, me ka maʻi Alzheimer a me ka dementia senile.
Ua hoʻāʻo nā kānaka ʻepekema i nā ʻiole keʻena hana, ua hānai ʻia kekahi pūʻulu i kahi meaʻai kiʻekiʻe i nā huahana hope glycation holomua, a ua hānai ʻia kekahi pūʻulu i kahi meaʻai me ka ʻai i hoʻemi ʻia o nā AGE pōʻino. Ma muli o ka ʻai ʻana o ka meaʻai "ʻino" i loko o ka lolo o nā ʻiole "ʻai ʻai", ua ʻike ʻia ka hōʻiliʻili ʻana o ka protein beta-amyloid pōʻino - ka hōʻailona nui o ka maʻi Alzheimer i loko o ke kanaka. I ka manawa like, hiki i ke kino o nā ʻiole i ʻai i ka meaʻai "maikaʻi" hiki ke hoʻopau i ka hana ʻana o kēia mea i ka wā o ka assimilation o ka meaʻai.
Ua mālama ʻia kekahi ʻāpana o ke aʻo ʻana i nā poʻe maʻi ʻelemakule (ma luna o 60 mau makahiki) i loaʻa i ka dementia. Ua hoʻokumu ʻia kahi pilina pili pono ma waena o ka ʻike o nā AGEs i loko o ke kino a me ka nāwaliwali o nā mana noʻonoʻo o ke kanaka, a me ka pilikia o ka maʻi puʻuwai. Ua ʻōlelo ʻo Kauka Helen Vlassara, ka mea nāna i alakaʻi i nā hoʻokolohua: "ʻO kā mākou ʻike ʻana i kahi ala maʻalahi e hōʻemi i ka pilikia o kēia mau maʻi ʻo ka ʻai ʻana i nā meaʻai haʻahaʻa i ka AGEs. Eia kekahi laʻana, he meaʻai kēia i hoʻomoʻa ʻia me ka wela haʻahaʻa me ka nui o ka wai - kahi ʻano kuke i ʻike ʻia e nā kānaka no nā kenekulia he nui.
Ua manaʻo ka poʻe ʻepekema e hoʻokaʻawale i ka maʻi o Alzheimer ma ke ʻano he "Type XNUMX Diabetes" i kēia manawa. pili pono kēia ʻano dementia i ka piʻi ʻana o ke kō i loko o ka lolo. Ua hoʻopau ʻo Kauka Vlassara: "Pono ʻia ka noiʻi hou e hoʻokumu i nā loulou pololei ma waena o nā AGE a me nā maʻi metabolic a me nā maʻi neurological. (I kēia manawa, hiki ke ʻōlelo ʻia hoʻokahi mea - Vegetarian)…ma ka hōʻemi ʻana i ka ʻai ʻana i nā meaʻai momona AGE, hoʻoikaika mākou i ka hana pale kūlohelohe e kūʻē i ka Alzheimer a me ka maʻi diabetes.
He kumu maikaʻi e noʻonoʻo ai no ka poʻe e noʻonoʻo nei i kahi ʻoki i hana maikaʻi ʻia "ka meaʻai olakino", a ma ka manawa like i mālama ʻia ka hiki ke noʻonoʻo pono!