Lohe pinepine mākou i ka huaʻōlelo "nohona noho" ma kahi pōʻaiapili, ʻōlelo ʻia ʻo ia ke kumu o ke olakino olakino a i ʻole ka hoʻomaka ʻana o ka maʻi. Akā no ke aha he mea weliweli loa kahi nohona noho? Ua ʻike wau i kahi ʻatikala i wehewehe nui iaʻu.
ʻIke ʻia hiki i ka hoʻoikaika kino ke hoʻoikaika i ka mokuʻāina o ka lolo, e hoʻoulu ai i ke kūkulu ʻana i nā hunaola hou a hana i nā loli ʻē aʻe. Ua kupu mai kahi noiʻi hou e hōʻike nei i ka immobility hiki ke hoʻomaka i nā loli i ka lolo e ka deforming kekahi mau neurons. A pili kēia i ka lolo wale nō, akā i ka puʻuwai pū kekahi.
Ua loaʻa ia ʻano ʻikepili i loko o kahi papa i hoʻopaʻa ʻia i nāʻiole, akā, e like me ka ʻepekema, he mea nui paha ia no nā kānaka. Hiki ke kōkua i kēia mau ʻike i ka wehewehe ʻana, i ka ʻāpana, no ke aha he maikaʻi ʻole nā nohona noho no ko mākou kino.
Inā hoihoi ʻoe i nā kikoʻī o ke aʻo ʻana, a laila e ʻike ʻoe iā lākou ma lalo, akā i ʻole e luhi iā ʻoe me nā kikoʻī, e haʻi wau iā ʻoe e pili ana i ke kumu.
ʻO nā hopena o ka hoʻokolohua, i paʻi ʻia ma The Journal of Comparative Neurology, e hōʻike ana i ka hana ʻole ʻana o ke kino i nā neurons i kekahi o nā wahi lolo. ʻO kēia ʻāpana ke kuleana o ka ʻōnaehana nūnē aloha, ka mea, i waena o nā mea ʻē aʻe, kaohi i ke kahe o ke koko ma o ka hoʻololi ʻana i ke kēkelē o ka liʻiliʻi o nā kīʻaha koko. I loko o kahi hui o nā ʻiole hoʻokolohua, ka mea i hoʻonele ʻia i ka hiki ke neʻe ikaika i mau pule he nui, ua ʻike ʻia ka nui o nā lālā hou i nā neurons o kēia ʻāpana o ka lolo. A ʻo kahi hopena, hiki i nā neurons ke hoʻonāukiuki i ka ʻōnaehana puʻuwai aloha iʻoi aku ka ikaika, hoʻohaunaele i ke kaulike i kāna hana a hiki i ka hoʻonui ʻana i ke kahe o ke koko a hāʻawi i ka ulu ʻana o nā maʻi puʻuwai.
ʻOiaʻiʻo, ʻaʻole nā kānaka nāʻiole, a he wahi liʻiliʻi kēia, kahi aʻo pōkole. Akā maopopo hoʻokahi hopena: ʻo kahi nohona nohona he hopena physiological nui.
Me he mea lā iaʻu ma hope o hoʻokahi pule i hala i ke anuanu, ka mea e pōpilikia ai, ʻaʻole ia he mea maʻa mau iaʻu a kaohi nui i koʻu noho ʻana i ke ea hou a me kaʻu hana ma ka laulā, makemake wau ma hope o kahi hoʻokolohua. A hiki iaʻu ke huki i kaʻu hopena ponoʻī mai kēia hoʻokolohua: ʻo ka nele i ka hana kino ka hopena maikaʻi ʻole i ka naʻau a me ke olakino laulā. ((
Nā mea hou aʻe e pili ana i ke kumuhana:
Ma mua o 20 mau makahiki i hala aku nei, manaʻo ka hapanui o nā ʻepekema i ka paʻa o ke ʻano o ka lolo me ka hoʻomaka ʻana o ke kanaka makua, ʻo ia hoʻi, ʻaʻole hiki i kou lolo ke hana hou i nā hunaola hou, e hoʻololi i ke ʻano o nā mea e ola nei, a i ʻole ma kekahi ʻano ʻaoʻao ʻē aʻe ke kūlana o kona lolo ma hope o ka ʻōpio. Akā i nā makahiki i hala iho nei, ua hōʻike ʻia ka noiʻi neurological i ka paʻa ʻana o ka lolo i ka plasticity, a i ʻole ka hiki ke loli, i loko o ko mākou ola. A, e like me ka ʻepekema, kūpono ka hoʻomaʻamaʻa kino no kēia.
Eia nō naʻe, ʻaneʻane ʻaʻohe mea i ʻike ʻia e pili ana i ka nele o ka hana kino i hiki ke hoʻohuli i ka loli o ke ʻano o ka lolo, a inā pēlā, he aha nā hopena. No laila, e alakaʻi i ke aʻo ʻana, ka ʻike e pili ana i ka mea i paʻi ʻia ma ka The Journal of Comparative Neurology, ua lawe nā ʻepekema mai ke Kula Kaiapuni Kula ʻo Wayne State he ʻumi mau iole. Noho lākou i ka hapalua o lākou i loko o nā hīnaʻi me nā huila e kaʻa ana, i hiki ai i nā holoholona ke piʻi i kēlā me kēia manawa. Makemake nāʻiole e holo, a ua holo lākou ma kahi o ʻekolu mile i ka lā ma kā lākou huila. Ua waiho ʻia nā koena iole i loko o nā hīnaʻi me nā kaʻa ʻole a koi ʻia lākou e alakaʻi i kahi "nohona noho."
Ma hope o ʻekolu mau mahina o ka hoʻokolohua, ua injected nā holoholona me kahi kala kūikawā i stains kikoʻī neurons i ka lolo. No laila, makemake nā ʻepekema e hōʻailona i nā neurons i ka rostral ventromedial ʻāpana o ka medulla oblongata o nā holoholona - kahi ʻimi ʻaʻole i ʻike ʻia o ka lolo e kaohi ana i ka hanu a me nā hana ʻike ʻole ʻē aʻe e pono ai no kā mākou ola.
Mālama ka rostral ventromedial medulla oblongata i ka ʻōnaehana ʻōnaehana aloha o ke kino, i waena o nā mea ʻē aʻe, kaohi i ke kahe o ke koko i kēlā me kēia minuke e ka hoʻololi ʻana i ke kēkelē o ka vasoconstriction. ʻOiai ʻo ka hapanui o nā ʻike ʻepekema e pili ana i ka rostral ventromedial medulla oblongata i hele mai mai nā hoʻokolohua holoholona, nā noiʻi kiʻi ʻana i nā kānaka e hōʻike nei he ʻāpana lolo ko mākou like a hana like ia.
Hoʻoponopono koke kahi ʻōnaehana ʻōnaehana aloha i ke kīkaha ʻana o nā kīʻaha koko a ʻae paha, e ʻae ana i ke kahe o ke koko kūpono, no laila hiki iā ʻoe ke ʻōlelo, holo i kahi ʻaihue a piʻi i waho o kahi noho keʻena me ka ʻole ʻole. Akā ʻo ka overreaction o ka ʻōnaehana nīnūnē ke kumu o nā pilikia, e like me ka ʻōlelo a Patrick Mueller, he loea pili o ka physiology ma ke Kulanui ʻo Wayne nāna i mālama i ka noi hou. Wahi a ia, ua hōʻike ʻia nā hopena ʻepekema hou loa o "ke kikowaena o ka sympathetic nerve system i ka maʻi o ka maʻi puʻuwai ma o ka hoʻoweliweli ʻana i nā kīʻaha koko, nāwaliwali a i ʻole pinepine hoʻi, i hiki ai i ke kiʻekiʻe o ke koko a me nā maʻi maʻi puʻuwai."
Kuhi nā kānaka ʻepekema ke hoʻomaka nei ka ʻōnaehana ʻōnaehana e hana hewa a weliweli inā loaʻa nā leka he nui (maliʻa paha) mai nā neurons i ka rostral ventrolateral medulla oblongata.
ʻO ka hopena, ke nānā nā ʻepekema i loko o ka lolo o kā lākou ʻiole ma hope o ka holo ʻana o nā holoholona a noho paha i mau hebedoma 12, ua ʻike ʻia ka ʻokoʻa ma waena o nā hui ʻelua i ke ʻano o kekahi o nā neurons i kēlā wahi o ka lolo.
I ka hoʻohana ʻana i kahi papahana hoʻomākaukau uila i kōkua ʻia e hana hou i loko o ka lolo o ka holoholona, ua ʻike nā kānaka ʻepekema i nā neurons i ka lolo o nāʻiole holo i ke ʻano like me ka hoʻomaka o ka hoʻopaʻa a hana maʻamau. Akā i ka nui o nā neurons i ka lolo o nāʻiole sedentary, ua ʻike ʻia kahi helu nui o nā antennae hou, nā lālā i kapa ʻia. Hoʻopili kēia mau lālā i nā neurons olakino i ka ʻōnaehana hopohopo. Akā, ʻoi aku ka nui o nā lālā o kēia mau neo ma mua o nā neurons maʻamau, e hoʻonui ana iā lākou i ka hoʻonāukiuki a me ka mākaukau e hoʻouna i nā leka uila ʻole i ka ʻōnaehana makaʻu.
I ka ʻoiaʻiʻo, ua loli kēia mau neurons i ke ala i lilo ai lākou i mea hoʻonāukiuki i ka ʻōnaehana puʻuwai aloha, hiki ke hoʻonui ʻia i ke kahe o ke koko a hāʻawi i ka ulu ʻana o ka maʻi puʻuwai.
He mea nui kēia ʻike ʻana, wahi a Kauka Müller, ʻoiai e hoʻonui ana i ko mākou ʻike i ka pehea, ma ka pae pae, hoʻonui ka hana ʻole i ka makaʻu o ka maʻi maʻi ʻōpū. Akā ʻoi aku ka pīhoihoi e pili ana i nā hopena o kēia mau aʻo ʻana ʻo ka immobility - e like me ka hana - hiki ke hoʻololi i ka hanana a me ka hana o ka lolo.
Sources:
NYTimes.com/blogs
ʻO ka ʻĀina National no ka ʻike ʻona ʻo Biotechnology