Hoʻokahi hapakolu o nā poʻe maʻi i loaʻa i ka maʻi maʻi ʻāʻī ua loaʻa i ka maʻi papillomavirus kanaka (HPV), ka hapa nui e pili ana me ka maʻi maʻi cervical, hōʻike ka Journal of Clinical Oncology.
ʻO nā maʻi me ka human papillomavirus (HPV) kekahi o nā mea maʻamau i ka honua. Hoʻouna ʻia ka maʻi maʻi ma o ka hoʻopili pololei ʻana i nā mucous membrane o nā ʻōpū, akā ʻo ka ʻili hoʻi a puni lākou. Manaʻo ka World Health Organization (WHO) i ka 80 pakeneka. Hoʻokumu ka poʻe moe kolohe i ka maʻi HPV i kekahi manawa o ko lākou ola. No ka hapanui o lākou, he manawa pōkole. Eia nō naʻe, ma kekahi pākēneka e lilo ia i mea maʻi, kahi e hoʻonui ai i ka pilikia o ka hoʻomohala ʻana i nā ʻano maʻi kanesa.
ʻOi aku ma mua o 100 mau ʻano subtypes i ʻike ʻia (i kapa ʻia he serotypes) o ka papillomavirus kanaka (HPV), he mau carcinogenic kekahi. ʻElua mau subtypes - HPV16 a me HPV18, nona ke kuleana no ka aneane 70 pakeneka. nā hihia o ka maʻi maʻi cervical.
Ua manaʻo ka poʻe loea o WHO ʻo ka maʻi HPV ke kuleana no ka aneane 100 pakeneka. nā hihia o ka maʻi maʻi maʻi cervical, a he 90 pakeneka. nā hihia maʻi ʻaʻai rectal, 40 pākēneka o nā maʻi kanesa o nā ʻōpū o waho - ʻo ia hoʻi ka vulva, vagina a me ka penis, akā no kekahi pākēneka o nā maʻi maʻi maʻi poʻo a me ka ʻāʻī, me 12% mau hihia o ka maʻi maʻi o ka larynx a me ka pharynx a kokoke. 3 pakeneka. nā maʻi maʻi waha. Aia kekahi mau haʻawina e hōʻike ana i ke komo ʻana o ka maʻi maʻi i ka ulu ʻana o ka umauma, ka māmā a me ka maʻi prostate.
Hōʻike nā haʻawina hou i ka piʻi ʻana o ka puʻu a me ka maʻi maʻi laryngeal e pili ana i ka maʻi HPV. A hiki i kēia manawa, ua manaʻo ʻia ka hoʻohana ʻana i ka waiʻona a me ka puhi paka ʻana i nā mea koʻikoʻi koʻikoʻi no kēia mau maʻi kanesa. Manaʻo ka poʻe ʻepekema ʻo ka piʻi ʻana o ka HPV i ka hoʻomohala ʻana i kēia mau maʻi maʻi maʻi e pili ana i ke kūʻokoʻa nui o ka moekolohe a me ka kaulana o ka wahine waha.
No ka hoʻāʻo ʻana i ka pilina ma waena o ka HPV a me ka maʻi kanesa o kekahi mau maʻi maʻi poʻo a me ka ʻāʻī, ua hana nā ʻepekema mai kahi hui honua i kahi noiʻi o 638 mau maʻi e loaʻa ana iā lākou, me ka maʻi maʻi o ka waha waha (180 mau maʻi), ka maʻi kanesa o ka oropharynx (135 mau maʻi) , ma'i 'a'ai o ka pharynx ha'aha'a / larynx (247 ma'i). Ua nānā pū lākou i nā poʻe maʻi me ka maʻi maʻi esophageal (300 poʻe). No ka hoʻohālikelike, ua hoʻāʻo ʻia nā kānaka olakino 1600. ʻO lākou a pau i komo i kahi noiʻi ʻEulopa lōʻihi e pili ana i ka pilina ma waena o ka nohona a me ka pilikia maʻi maʻi - European Prospective Investigation Into Cancer and Nutrition.
ʻO nā laʻana koko i hāʻawi ʻia a pau i ka hoʻomaka ʻana o ke aʻo ʻana ʻoiai lākou e ola ana, ua nānā ʻia no nā antibodies i nā protein HPV16 a me nā ʻano subtypes papillomavirus kanaka carcinogenic e like me HPV18, HPV31, HPV33, HPV45, HPV52, a me HPV6 a me HPV11. ʻO ke kumu maʻamau o ka maʻi maʻi maʻi akā pilikia (ka mea i kapa ʻia ʻo genital warts), a hiki ʻole ke kumu i ka maʻi maʻi vulvar.
ʻO nā laʻana maʻi maʻi ma ka awelika ʻeono makahiki, akā ʻoi aku kekahi ma mua o 10 mau makahiki ma mua o ka maʻi ʻana.
Ua ʻike ʻia he 35 pakeneka. Ua ʻike ʻia nā poʻe maʻi maʻi maʻi ʻaʻai oropharyngeal i nā antibodies i kahi protein koʻikoʻi o ka HPV 16, i hoʻopau ʻia ʻo E6. Hoʻopau ia i ka protein kuleana no ka pale ʻana i ke kaʻina neoplastic i loko o nā pūnaewele a no laila ke kōkua nei i kona hoʻomohala ʻana. ʻO ka loaʻa ʻana o nā antibodies i ka protein E6 i loko o ke koko e hōʻike pinepine i ka ulu ʻana o ka maʻi kanesa.
No ka hoʻohālikelike, i loko o ka pūʻulu mana ka pākēneka o ka poʻe me nā antibodies i ke koko he 0.6%. ʻAʻohe pilina ma waena o ko lākou hele ʻana a me nā maʻi maʻi poʻo a me nā ʻāʻī ʻē aʻe i komo i loko o ke aʻo ʻana.
Ua hoʻoikaika ka poʻe noiʻi i ka pilina ma waena o ka hiki ʻana o kēia mau antibodies a me ka maʻi maʻi oropharyngeal no nā poʻe maʻi i loaʻa mai kahi hoʻohālike koko ma mua o 10 mau makahiki ma mua o ka maʻi kanesa.
ʻO ka mea e mahalo ai, i waena o nā poʻe maʻi me ka maʻi kanesa oropharyngeal a me ka loaʻa ʻana o nā antibodies anti-HPV16, ua loaʻa kahi haʻahaʻa haʻahaʻa o ka make ma muli o nā kumu like ʻole ma mua o nā maʻi me ka ʻole o nā antibodies. ʻElima mau makahiki ma hope o ka hōʻoia ʻana, 84 pakeneka e ola mau ana. kanaka mai ka hui mua a me 58 pakeneka. ʻo kekahi.
Ke hāʻawi nei kēia mau hopena kamahaʻo i kekahi mau hōʻike e hiki ai i ka maʻi HPV16 ke kumu nui o ka maʻi maʻi oropharyngeal, wahi a Kauka Ruth Travis o ke Kulanui o Oxford.
Ua ʻōlelo ʻo Sara Hiom mai ka Cancer Research UK ma kahi ninaninau me ka BBC ua laha loa nā maʻi HPV.
ʻO ka moe kolohe ʻana me ka palekana e hoʻohaʻahaʻa i ka pilikia o ka loaʻa ʻana o ka maʻi a i ʻole ka hāʻawi ʻana i ka HPV i kekahi, akā ʻaʻole e pale pono nā condom iā ʻoe mai ka maʻi, wahi āna. Ua ʻike ʻia ʻo ka maʻi maʻi i loaʻa ma ka ʻili ma ka ʻāpana genital hiki ke lilo i kumu o ka maʻi.
Ua hoʻokūpaʻa ʻo Hiom ʻaʻole ʻike ʻia inā hiki i nā lāʻau lapaʻau i hoʻohana ʻia i kēia manawa no ka pale ʻana i ka maʻi kanesa cervical i nā kaikamahine ʻōpio (ua ʻae ʻia kekahi o lākou no nā keikikāne e pale i ka maʻi maʻi genital a me ka maʻi kanulau penile) hiki ke hōʻemi i ka hopena o ka maʻi maʻi oropharyngeal. Inā hōʻoia ka noiʻi i kēia, hiki ke hoʻohana nui ʻia i ka pale ʻana i nā neoplasms malignant. (PAP)
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