ʻO nā lāʻau lapaʻau e kāohi i ka hana o ka protein ʻōnaehana pale - gamma interferon i ka hoʻomohala ʻana o ka melanoma - kahi maʻi maʻi ʻili weliweli - e like me nā ʻepekema US ma ka puke pai Nature.
ʻO ka ʻike ʻana i ke kukui ultraviolet a me ka radiation nā kumu nui ʻelua o ka ulu ʻana o ka melanoma - ka maʻi maʻi ʻili ʻino loa. ʻO ka mea pōʻino, a hiki i kēia manawa, ʻaʻole i hoʻomaopopo piha ʻia nā ʻano molekala o ka ulu ʻana o kēia maʻi kanesa.
Ua aʻo ʻo Glenn Merlino a me nā hoa hana mai ka National Cancer Institute ma Bethesda i nā hopena o ka radiation UVB i nā ʻiole. Ua hōʻike nā kānaka ʻepekema ʻo UVB ka mea e kahe ai nā macrophages i ka ʻili. ʻO nā macrophages kekahi ʻano o ke koko keʻokeʻo keʻokeʻo, nā cell e hana ana i ka interferon gamma, he protein e hōʻailona ai i ka ulu ʻana o ka melanoma.
ʻO ka pale ʻana i ka hana o ka interferon gamma (ʻo ia hoʻi ka interferon type II) me ke kōkua o nā antibodies kūpono e kāohi i ka ulu ʻana o nā ʻili ʻili a me ka ulu ʻana o ka maʻi kanesa, ʻaʻohe hopena o ka hana interferon I.
Hoʻomaopopo ʻia nā interferon Type I he mau protein anti-cancer a ʻo kekahi o lākou, interferon alpha, hoʻohana ʻia e mālama i ka melanoma. ʻO ka loaʻa ʻana o ka gamma interferon ka hopena ʻē aʻe a hāpai i ka ulu ʻana o ka maʻi kanesa. ʻO ka pale ʻana i ka interferon gamma a i ʻole nā protein e pili ana i mea e ʻike ʻia he pahuhopu maikaʻi ia no ka maʻi melanoma. (PAP)