Klinefelter's Syndrome (syndrome 47, XXY) - nā kumu, nā hōʻailona, ​​​​ka lāʻau lapaʻau

Maikaʻi i hōʻoia ʻia

ʻO ka maʻi maʻi o Klinefelter (ʻike ʻia ʻo 47, XXY a i ʻole hypergonadotrophic hypogonadism) he maʻi hoʻoilina i loaʻa i nā kāne i loaʻa i nā ʻano genetic me kahi chromosome X hou i loko o nā mea āpau a i ʻole kekahi o nā keena o ke kino. Ma kahi o ka loaʻa ʻana o 2 chromosomes sex - hoʻokahi chromosomes X a me hoʻokahi Y, e like me ke ʻano o ke kāne olakino, loaʻa i ka poʻe me ka maʻi Klinefelter ʻekolu mau chromosomes sex - 2 X chromosomes a me hoʻokahi Y chromosomes. Manaʻo nā kānaka ʻepekema ʻo 47, XXY Syndrome kekahi o nā maʻi maʻamau i nā loli chromosomal e kū nei i loko o ke kanaka. ʻO ke kumu kumu o nā hōʻailona o kēia maʻi he haʻahaʻa haʻahaʻa haʻahaʻa haʻahaʻa haʻahaʻa haʻahaʻa testosterone, i hui pū ʻia me nā kiʻekiʻe kiʻekiʻe o nā gonadotrophins (ka nui o ka FSH).

ʻOiai ʻo kēlā me kēia kāne i loaʻa i kēia maʻi he X chromosome hou, ʻaʻole i loaʻa i kēlā me kēia kanaka nā hōʻailona a pau i helu ʻia ma lalo nei. Eia kekahi, ʻo ka paʻakikī o kēia mau hōʻailona e pili ana i ka helu o nā cell me ka helu abnormal o nā chromosomes, ke kiʻekiʻe o ka testosterone i ke kino, a me ka makahiki i ʻike ʻia ai ka maʻi.

ʻO nā hōʻailona o ka maʻi o Klinefelter e pili ana i ʻekolu mau wahi o ka ulu ʻana:

1. kino,
2. ʻŌlelo,
3. Pūʻulu.

Klinefelter Syndrome - Hoʻoulu kino

I ka wā kamaliʻi, nāwaliwali pinepine ka ʻiʻo a me ka ikaika. Hiki i nā pēpē i hoʻopilikia ke hoʻomaka e kolo, noho i lalo a hele kaʻawale ma hope o nā pēpē olakino. Ma hope o 4 mau makahiki, ʻoi aku ka lōʻihi o nā keikikāne me ka maʻi Klinefelter a ʻoi aku ka maikaʻi o ka hoʻonohonoho ʻana. Ke hiki lākou i ka wā ʻōpio, ʻaʻole hana ko lākou kino i ka nui o ka testosterone e like me ka poʻe olakino. Hiki i kēia ke alakaʻi i nā musculature nāwaliwali, liʻiliʻi ka lauoho maka a me ke kino. I ka wā ʻōpiopio, ua hoʻonui ʻia ka umauma o nā keikikāne (gynecomastia) a me ka palupalu o ka iwi.

I ka wā e hiki ai i ke kanaka makua, ua like paha nā kāne me ka maʻi maʻi me nā kānaka olakino, ʻoiai ʻoi aku ka lōʻihi ma mua o nā poʻe ʻē aʻe. Eia kekahi, ʻoi aku ka nui o ka hoʻomohala ʻana i nā maʻi autoimmune, ka maʻi maʻi umauma, nā maʻi venous, osteoporosis a me ka pala o ka niho.

Ma hope o ka ʻōpio, ʻo nā hōʻailona maʻamau o ka poʻe i loaʻa i ka maʻi Klinefelter:

- ulu nui,

- ka ʻili ʻeleʻele,

- nā ʻiʻo i hoʻomohala maikaʻi ʻia (ka mea i kapa ʻia ʻo eunchoid body structure),

- lauoho kino liʻiliʻi: lauoho maka palupalu, lauoho pubic o ke ʻano wahine a puni ka genitalia waho,

- nā testicles liʻiliʻi me ka hoʻolālā penis kūpono,

- hoʻemi libido,

- gynecomastia bilateral.

Hiki i nā kāne me ka maʻi Klinefelter ke alakaʻi i ke ola wahine maʻamau. Eia naʻe, ma muli o ka hiki i ko lākou kino ke hoʻohua liʻiliʻi a ʻaʻohe sperm, 95 a 99% o lākou he sterile.

Klinefelter Syndrome - ʻŌlelo

I ka wā kamaliʻi, 25 a 85% o ka poʻe me Klinefelter syndrome ka pilikia o ka ʻōlelo. Hoʻomaka lākou e haʻi i kā lākou mau huaʻōlelo mua ma mua o ko lākou mau hoa, pilikia ka haʻi waha ʻana i ko lākou mau pono a me nā manaʻo, a me ka heluhelu ʻana a me ka hoʻoponopono ʻana i ka ʻike a lākou e lohe ai. Ma ke ʻano he poʻe mākua, ʻoi aku ka paʻakikī o ka hoʻopau ʻana i kā lākou mau hana heluhelu a kākau, akā ʻo ka hapa nui o lākou e hana a loaʻa ka kūleʻa i ko lākou ola hana.

Klinefelter Syndrome - Ke ola kaiaulu

I ka wā kamaliʻi, noho mālie nā keiki me ka maʻi Klinefelter a ʻaʻole e komo i ka manaʻo o ka poʻe a puni lākou. Ma hope aku, emi iho ka hilinaʻi iā lākou iho a me ka hana, a hōʻike i ka makemake nui e kōkua a hoʻolohe ma mua o kā lākou mau hoa.

I ka wā ʻōpio, hilahila a noho mālie nā keikikāne, ʻo ia ke kumu e loaʻa pinepine ai nā pilikia "kūpono" i kā lākou hui.

I ka hiki ʻana i ka makahiki o ka hapa nui, alakaʻi lākou i kahi ola maʻamau, hoʻomaka i nā ʻohana a loaʻa nā hoaaloha. Hiki iā lākou ke komo i nā pilina pili kaiaulu maʻamau.

Klinefelter's Syndrome - Hiki ke mālama ʻia kēia maʻi?

ʻO Klinefelter's Syndrome he mea hānau ʻole a no laila ʻaʻole hiki ke hoʻōla ʻia. Eia naʻe, hiki ke hoʻohaʻahaʻa i kona mau hōʻailona. No kēia kumu, hoʻohana ʻia nā lāʻau lapaʻau he nui, e like me ke kino, ka waha, ke ʻano, ka psychotherapy a me nā ʻohana. I kekahi manawa kōkua lākou i ka hoʻohaʻahaʻa ʻana i nā hōʻailona e like me ka nawaliwali o ka ʻiʻo, nā pilikia ʻōlelo a i ʻole ka haʻahaʻa haʻahaʻa. Hoʻemi ʻia ka Pharmacotherapy i ka hoʻohana ʻana i ka testosterone replacement therapy (TRT). Hāʻawi ia iā ʻoe e hoʻihoʻi i ke kiʻekiʻe o kēia hormone i loko o ke koko i nā waiwai maʻamau, ʻo ia ka mea e ʻae ai i ka ulu ʻana o nā ʻiʻo, hoʻohaʻahaʻa i ka leo, a me ka ulu ʻana o ka lauoho nui.

ʻO kekahi o nā mea nui e hoʻoholo ai i ka maikaʻi o ka mālama ʻana ʻo ia ka manawa mua o kāna hoʻokō.

Maopopo iā ʻoe kēlā:

Inā hana kekahi kumu e hōʻino i ka spermatogenesis (ke kaʻina hana o ka hoʻokumu ʻana i ka sperm) i nā hōʻike o kahi keikikāne hānau, ʻo ia ka mea i kapa ʻia ʻo Klinefelter syndrome. Ua like nā hōʻailona me ka maʻi Klinefelter maoli i kūkākūkā ʻia ma luna, akā ʻaʻole hōʻike ka hoʻāʻo karyotype i ka loaʻa ʻana o kahi chromosome X sex keu.

Kikokikona: MD Matylda Mazur

ʻO ka ʻike o ka pūnaewele medTvoiLokony i manaʻo ʻia e hoʻomaikaʻi, ʻaʻole e hoʻololi i ka pilina ma waena o ka mea hoʻohana pūnaewele a me kā lākou kauka. Hoʻolālā ʻia ka pūnaewele no ka ʻike a me ka hoʻonaʻauao wale nō. Ma mua o ka hahai ʻana i ka ʻike loea, i ka ʻōlelo aʻoaʻo olakino, aia ma kā mākou Pūnaewele, pono ʻoe e nīnau i ke kauka. ʻAʻole lawe ka Luna Hoʻokele i nā hopena ma muli o ka hoʻohana ʻana i ka ʻike i loaʻa ma ka Pūnaewele.