Hiki i ka maʻi o Paget ke hoʻopili hoʻokahi a ʻoi paha iwi. Hoʻopili wale ia nā iwi i pā mua ʻia (ʻaʻohe hiki ke hoʻonui ʻia ma nā iwi ʻē aʻe).

ʻOi pinepine asymptomat, ʻike ʻia e ka manawa ma nā hōʻike radiographic i lawe ʻia no kekahi kumu ʻē aʻe.

Hiki i kekahi mau hōʻailona hoʻokolohua ke hōʻike i ka maʻi a hōʻoia i ke kuhikuhi o nā loiloi radiological:

-ʻeha iwi

-na ʻaila iwi : kūlike ʻole lākou a lohi (hōʻailona o ka pāpale e hypertrophy [hoʻonui i ka nui] o ka iwi poʻo, ka lāʻau tibber, he pālahalaha o ka thorax, deformation o ka iwi kuamoʻo [kyphosis])

-pilikia vasomoteurs (nā kīnā ʻole o ke kīʻaha koko) kuleana no ka hyperemia (ka nui o ke komo ʻana o ke koko i mea ʻulaʻula) o ka ʻili aʻe i nā ʻiʻo iwi

E hoʻomaopopo he ʻaʻohe deterioration i ke ʻano maʻamau.

ʻO nā iwi i hoʻopilikia ʻia e ka maʻi nā iwi o ke pelvis, ka dorsal a me ka lumbar vertebrae, ka sacum, ka femur, ka iwi poʻo, ka tibia.

ka nā māmā-x hana i kahi mea hiki ke hoʻomālamalama i nā hōʻailona ʻano o ka maʻi.

- nā mea kūpono ʻole o ke kinona: hypertrophy iwi (hoʻonui i ka nui)

- nā hanana kūpono ʻole: ka mānoanoa o nā corticals (nā paia iwi)

-o nā anomalies: heensogeneous condensation o ka iwi e hāʻawi ana i kahi pale

Hiki i ka iwi scintigraphy ke hoʻokūkala i ka hyperfixation ikaika ma nā iwi i hoʻopilikia ʻia. ʻO ka makemake nui o kēia hoʻokolohua ʻana e ʻike i nā iwi i hoʻopili ʻia e ka maʻi. Eia naʻe, ʻaʻohe pono e hana hou ia i ka wā o ka nānā ʻana a me ka mālama ʻana i ka mea maʻi.

Hoʻohālikelike ka hoʻonui ʻana o nā phosphates alkaline i ke koko i ka nui a me ka hana o ka maʻi. Hōʻike ia i ka hana ikaika o ka hoʻokumu iwi. He maʻamau paha kēia mahele inā hoʻokau ʻia ka maʻi i hoʻokahi iwi.

Hoʻonui ʻia nā hana o nā crosslaps (i kapa ʻia ʻo CTx a i ʻole NTx) a me pyridinolines i ke koko a i ʻole ka mimi a hōʻike i ka hana o ka luku iwi.

ʻAʻole like me ka scan iwi, pono kēia mau scans no ka nānā ʻana i ka maʻi ma lalo o ka lāʻau. E like me ia, hana ʻia kēlā me kēia 3 a 6 mau mahina.

E hoʻomaopopo i:

-calcemia (pae calcium i loko o ke koko) maʻamau maʻamau. Hiki ke hoʻonui ʻia i ka hanana o ka immobilization hoʻolōʻihi a i ʻole hyperparathyroidism e pili ana.

-ʻo ka helu sedimentation ka mea maʻamau.

ka pilikia loli ka maʻi mai kekahi mea maʻi a i kekahi ʻē aʻe a ʻo kēia ka papa penei:

-haʻi ʻōlelo : ka mea nui e pili ana i ka uha a me ke kuli, pili lākou i nā deformities o nā wēlau o nā iwi i hoʻokumu ʻia e ka maʻi a he kuleana no ka ʻeha, deformation a me ka hana impotence

-iwi : nā iwi haʻi nāwaliwali

ʻOi aku ka liʻiliʻi, hiki i nā pilikia ke ala aʻe:

-ke aʻalolo : pili i ke kaomi ʻana o nā ʻalolo e ka deformation o nā iwi. No laila, hiki ke nānā i ka kuli pinepine i nā ʻāina ʻelua (pili i nā pepeiao ʻelua), paraplegia (hiki ke mālama ʻia)

-Puʻuwai : maikaʻi ʻole o ka puʻuwai

Exceptionally, i ka hanana o ka malignant hikoko hiki ke hana ma luna o ka iwi loli i ka maʻi (humerus a me femur). ʻO ka hoʻonui ʻia o ka ʻeha a me nā radiographic abnormalities e ʻōlelo paha i kēia ʻike, a ʻo ia wale nō e hōʻoia me ka ʻoiaʻiʻo e ka hana ʻana i kahi biopsy.

ʻAʻole pono e huikau ka maʻi o Paget me:

- hyperparathyroidism

-o nā metastases iwi mai ka umauma maʻi ʻaʻai a i ʻole ka maʻi ʻaʻai prostate

- myeloma maha (i kapa ʻia ʻo ka maʻi ʻo Kahler)