Hoʻonohonoho ʻo LDH i kahi papa o nā enzymes, Lactase dehydrogenases. Loaʻa lākou iā lākou ma nā wahi āpau o ke kino, inā ma nā mākala (a ʻo ka puʻuwai pū kekahi), i nā aʻa o nā akemā a i nā ʻula o ke koko. ʻO ka enzyme kahi protein i hana i ka catalyze reaksi i loko o ke kino, i nā huaʻōlelo ʻē aʻe e hoʻonāuki iā lākou a i ʻole e wikiwiki i kahi kaʻina hana lohi loa.

Nui a hewahewa nā ʻano, a i ʻole isoenzymes, i kaha ʻia e ka helu e like me ko lākou wahi. Pēlā ka poʻe o ka puʻuwai a i ʻole ka lolo i loaʻa i ke kūlana o ka LDH 1 a me ka 2, ʻoiai ka poʻe o nā pelaha a me nā lymph node he LDH3, nā mea o ka ate LDH 4 a me nā ʻili LDH5.

ʻO ka hana a LDH i loko o ke kino e catalyze i ka hoʻololi o pyruvate i lactate, a ʻo ka hope. ʻO kēia mau ʻakika i kahi kuleana o ka hoʻohuli ikehu ma waena o nā hunaola.

Hoʻomaopopo e kāhea ʻia ia lactate dehydrogenase, a i ʻole lactic dehydrogenase, a i kekahi manawa e hōʻailona ʻia e LD.

ʻO ka hoihoi olakino o nā enzyme LDH ma luna o nā mea āpau e ʻike ai i ka piʻi nui ʻole o kā lākou alo. ʻO ka maʻamau, mālama ʻia ʻo LDH i loko o nā kino o ke kino. Akā inā ua hōʻino ʻia nāʻaʻaʻa, e ninini lākou, a no laila catalyze aʻoi aku ka nui o ka pyruvate i lactate.

ʻO ka hoʻomaopopo ʻana iā lākou i nā wahi kikoʻī a i ʻole ka nānā ʻana i kā lākou hana i loko o ke kino e hiki ai ke hoʻoholo i kahi i loaʻa i ka hōʻino ʻia o ka cell, a i ʻole e nānā i ka nui. He mea kūpono nō hoʻi ia no ka ʻike ʻana i kahi ʻano o nā maʻi, mai ke anemia a i ke kanesa (e nānā i ka "Interpretation of the LDH hopena").

Lawe ʻia ka ninaninau ʻana o ke anawaena LDH e ka laʻana koko maʻalahi. ʻO ke kikoʻī, e kālailai nā keʻena hoʻokolohua i ka serum, ka wai i kahi e ʻauʻau ai nā mea pili koko e like me nā waiʻulaʻula. ʻOiai ʻo ka hope i loaʻa he mau enzyme LDH i loko o ko lākou mau puʻuwai, aia ma luna o nā lāʻau āpau o ke serum e helu ana i ka hoʻoholo inā he ʻokoʻa ka pae a ʻaʻole paha.

Loiloi ʻia ke kumukūʻai kūmole no ka hoʻāʻo o ka LDH enzyme ma 120 a 246 U / L (nā wae no kēlā me kēia lita).

I mea e nānā ai i ka hoʻokolokolo ʻana, hiki i ke kauka lapaʻau ke kālailai i nā hopena i hāʻawi ʻia e ka hale hana, a ʻike paha i nā ʻano maʻi like ʻole i ka mea maʻi. ʻO ka pinepine, pono e hoʻopili i kēia hopena me ka pae o nā ʻenemika ʻē aʻe a i ʻole nā ​​waikawa, no ka mea ʻo ka hoʻonui maʻalahi a hoʻemi ʻia paha o ka LDH hiki ke loaʻa nā kumu like ʻole. Aia nā ʻano ʻokoʻa o ka wehewehe ʻana.

Inā kiʻekiʻe ka pae LDH:

• Anemia

ʻO ka pinepine hiki ke lilo i pernicious (i kapa ʻia ʻo ka maʻi ʻo Biermer), a i ʻole hemolytic anemia. I ka hope, hoʻopili nā autoantibodies i nā hunaola ʻulaʻula a luku iā lākou, kahi e hoʻonui ai i ke kiʻekiʻe o ka LDH i loko o ke koko.

• Nā ʻōiwi: kekahi mau ʻano maʻi ʻaʻai e like me neoplasias e pili pū ʻia me ka piʻi wikiwiki ʻana i ka LDH.
• Infarction: Ma hope o ka infoccial myocardial, pili me ka hōʻino ʻana i nā aʻa o ka puʻuwai, ʻike ʻia ka hoʻonui ʻia o nā kiʻekiʻe LDH ma loko o 10 mau hola. E hāʻule hou ka helu i nā pule ʻelua aʻe.
• AVC (like manaʻo me infactus)
• Pancreatitis
• Nā maʻi ʻino a me nā ʻōpū
• Mononukleosis
• Emperor pulmonary
• ʻO ka angina pectoris
• ʻO ka maʻi dicstrophy
• Hepatitis (ʻawahia a mea ālai paha)
• Myopathy (kaukaʻi ʻia i kahi o ka maʻi)

Inā haʻahaʻa a maʻamau paha ka pae LDH:

I kēia hihia ʻaʻole pilikia, a i ʻole ʻike ʻia e kēia mea, i ka meaola.

Hopohopo i ke koko.

ʻO ka ʻokoʻa, hemolysis (ka haki ʻana o nā hunaola ʻulaʻula i loko o ke koko) i ka manawa o ka hoʻāʻo hiki ke hana i kahi hopena maikaʻi ʻole. E laha maoli nō ka LDH i loko o nā hunaola ʻulaʻula, a no laila e hoʻololi i ka hopena.

Ma hope o ka hoʻokolokolo ʻana i ka pae LDH, e hoʻouna ʻia nā hopena i kāu kauka i hiki ke kamaʻilio hou me lākou inā pono. Inā hōʻike nā hopena i ke kū ʻana o kahi maʻi, a laila e hāʻawi wale ʻia ʻoe i ka loea i nīnau ʻia.

I ka hanana ʻana o ka maʻi ʻaʻai, hiki i ka nānā mau ʻana o ka pae LDH ke hōʻoia i ke kūleʻa ʻana o ka maʻi ʻaʻai ʻole, i mea e ʻike ai inā e luku maoli ʻia nā pūnana pahuhopu a i ʻole hoʻouka kaua paha i nā ʻāpana ʻē aʻe o ke kino.