Hāʻawi ʻia nā makuahine i ka nānā nui. Akā, hōʻike ʻia ka noiʻi ʻana i ka ʻai ʻana o ka makua kāne ma mua o ka hāpai ʻana, hiki ke pāʻani i ke ʻano koʻikoʻi i ke olakino o nā keiki. Ua hōʻike ʻia nā noiʻi hou no ka manawa mua he mea koʻikoʻi nā pae paternal folate no ka ulu ʻana a me ke olakino o nā keiki e like me ka makuahine.
Manaʻo ka mea noiʻi ʻo McGill e nānā pono nā makua kāne i ko lākou nohona a me kā lākou ʻai ma mua o ka hāpai ʻana i mau makuahine. Aia nā hopohopo e pili ana i nā hopena lōʻihi o nā meaʻai Western o kēia manawa a me ka palekana o ka meaʻai.
Ua nānā ka noiʻi i ka huaʻa B9, i kapa ʻia ʻo folic acid. Loaʻa ia i nā lau ʻōmaʻomaʻo lau, cereals, huaʻai a me nā ʻiʻo. Ua ʻike maopopo ʻia, i mea e pale ai i ka hāʻule ʻana a me nā hemahema o ka hānau ʻana, pono e loaʻa i nā makuahine ka nui o ka waikawa folic. Aneane ʻaʻole i nānā ʻia ka hopena o ka ʻai a ka makua kāne i ke olakino a me ka ulu ʻana o nā keiki.
"ʻOiai ke hoʻohui ʻia nei ka waikawa folic i nā meaʻai like ʻole, ʻaʻole hiki i nā makuakāne e hiki mai ana e ʻai i nā meaʻai momona nui, ʻai i ka meaʻai wikiwiki, a i ʻole ka momona, ʻaʻole hiki iā lākou ke komo a hoʻohana pono i ka waikawa folic," wahi a nā ʻepekema mai Kimmins Research Group. "ʻO ka poʻe e noho ana ma ke kūkulu ʻākau o Kanada a i ʻole nā wahi ʻē aʻe i mālama ʻole ʻia o ka honua e pilikia paha i ka nele o ka waikawa folic. A i kēia manawa ua ʻike ʻia he hopena koʻikoʻi kēia no ka embryo.
Ua hōʻea nā mea noiʻi i kēia hopena ma o ka hana ʻana me nā ʻiole a me ka hoʻohālikelike ʻana i nā keiki a nā makua kāne me ka nele o ka folic acid i ka meaʻai me nā keiki a nā makua kāne i loaʻa i ka nui o ka vitamina. Ua ʻike lākou ua pili ka hemahema o ka paternal folic acid me ka piʻi ʻana o nā kīnā hānau o nā ʻano like ʻole i kāna mau keiki, i hoʻohālikelike ʻia me nā keiki a nā ʻiole kāne i hānai ʻia i ka nui o ka waikawa folic.
"Ua kāhāhā nui mākou i ka ʻike ʻana i ka piʻi ʻana o kahi kokoke i 30 ka nui o nā hemahema hānau i loko o ka ʻōpala o nā kāne i nele ka pae o ka folate," wahi a Kauka Roman Lambrot, kekahi o nā ʻepekema i komo i ka noiʻi. "Ua ʻike mākou i kekahi mau anomalies skeletal koʻikoʻi e pili ana i nā defects craniofacial a me nā deformities spinal."
ʻO kahi haʻawina a ka hui Kimmins e hōʻike ana aia kekahi mau ʻāpana o ka sperm epigenome e pili ana i ka nohona a me ka meaʻai. A ʻike ʻia kēia ʻike i ka palapala i kapa ʻia epigenomic, e pili ana i ka hoʻomohala ʻana o ka embryo, a hiki ke hoʻopili i ka metabolism a me ka ulu ʻana o nā maʻi i nā keiki i ka wā lōʻihi.
Hiki ke hoʻohālikelike ʻia ka epigenome i kahi hoʻololi e hilinaʻi ana i nā hōʻailona mai ke kaiapuni a pili pū kekahi i ka ulu ʻana o nā maʻi he nui, e like me ke kanesa a me ka maʻi diabetes. Ua ʻike mua ʻia ka hana ʻana o ka holoi ʻana a me ka hoʻoponopono ʻana i ka epigenome i ka wā e ulu ai ka sperm. Ua hōʻike ʻia kahi noiʻi hou me kahi palapala hoʻomohala, lawe pū ka sperm i ka hoʻomanaʻo o ke kaiapuni o ka makuakāne, ka meaʻai a me ke ʻano o ka nohona.
"Ke hōʻike nei kā mākou noiʻi e pono i nā makua kāne ke noʻonoʻo i ka mea a lākou e hoʻokomo ai i loko o ko lākou waha, ka mea a lākou e puhi ai a me nā mea a lākou e inu ai, a e hoʻomanaʻo he mau kahu hānai lākou," i hoʻopau ai ʻo Kimmins. "Inā holo nā mea a pau e like me kā mākou i manaʻo ai, ʻo kā mākou hana aʻe e hana pū me nā limahana o ke keʻena ʻenehana reproductive a aʻo i ke ʻano o ke ʻano o ka nohona, ka meaʻai a me nā kāne momona i ke olakino o kā lākou mau keiki."